the study was carried out in zoo animals at islamabad zoo, pakistan to know the prevalence of bovinetuberculosis. an overall prevalence of 3.3% was recorded in zoo animals with 3.6% in bovidae, 3.2% incervidae and 0% in equidae families. the positive animals included spotted deer (1/3; 95% ci = 0.84,90.57), chinkara gazella (1/5; 95% ci = 0.51, 71.64) and blackbuck gazelle (1/30; 95% ci = 0.08,...

BACKGROUND Despite certain drawbacks, the tuberculin skin test (TST) remains in widespread use. Important advantages of the TST are its low cost, simplicity and interpretation based on extensive published literature. However, TST specificity is reduced by bacille Calmette-Guérin (BCG) vaccination and exposure to non-tuberculous mycobacteria (NTM). METHODS To estimate TST specificity, we revie...

BACKGROUND The HIV/AIDS epidemic has caused an excess of tuberculosis cases in Spain and in other countries, but its impact on tuberculosis infection is less well understood. This study presents a massive screening undertaken to estimate the prevalence of tuberculous infection in a cohort of primary school entrants. The evolution of the risk of infection is studied by comparison with previous d...

The average annual risk of infection with Mycobacterium tuberculosis is a calculated average from an observed prevalence of infection, approximating the incidence of infection. It has the potential to be informative about the extent of transmission in a community. Where serial surveys are available, secular trends in transmission might be ascertained. The prerequisite for calculating the averag...

OBJECTIVE To investigate the influence of BCG vaccination or revaccination on tuberculin skin test reactivity, in order to guide the correct interpretation of this test in a setting of high neonatal BCG vaccination coverage and an increasing BCG revaccination coverage at school age. METHODS We conducted tuberculin skin testing and BCG scar reading in 1 148 children aged 7-14 years old in the ...