With growing awareness of the importance of pain control in all procedures, the use of lidocaine-prilocaine cream (EMLA) for all ages is increasing. Lidocaine-prilocaine cream has been implicated as a cause of methemoglobinemia. Diagnostic clues may be oxygen-resistant cyanosis and an oxygen "saturation gap" between arterial blood saturation and pulse oximetry. Treatment with intravenous methyl...

the purpose of the present article is to carry out a review of the literature on two local anesthetic agents, which are the most commonly used drugs in dental procedures. it would provide a clear concept about the local anesthetics, their dosages and exact usage in dental surgeries.

We found a small but significant increase in methaemoglobin concentration in 1-6 year old children after routine administration of 5 g of prilocainelignocaine cream before surgery. Although the peak methaemoglobin concentration observed was well within safe limits, the finding of an increased concentration 24 hours after administration suggests that cumulative effects may occur in children rece...

BACKGROUND Pain of circumcision is only partially relieved by single modalities, such as penile nerve block, lidocaine-prilocaine cream, and sucrose pacifiers. OBJECTIVE To assess the effectiveness of a combination of interventions on the pain response of infants undergoing circumcision. METHODS Cohort study. Group 1 included infants circumcised using the Mogen clamp and combined analgesics...

We report what we think is the first case of localised angioedema of the glans penis as a result of contact allergy to prilocaine in EMLAP cream. We also propose a new term, contact angioedema for this condition.

BACKGROUND Pain is a common adverse effect of dermatological laser procedures. Currently, no standard topical anaesthetic cream exists for deeper dermal laser procedures. OBJECTIVES To compare the efficacy of lidocaine/tetracaine cream and lidocaine/prilocaine cream in reducing self-reported pain during deeper dermal laser treatment of acne keloidalis nuchae (AKN) and tattoos. METHODS We co...

OPICAL ANESTHESIA REPRESENTS A T c o m m o d y used anesthetic technique for a variety of endoscopic procedures.'4 In general, local anesthesia for endoscopy is a safe and effective procedure.g However, it has been shown that certain local anesthetics, such as tetracaine, are rapidly absorbed from the mucous membranes of the respiratory tract and can lead to severe toxic effects in man.' Thus, ...