Grapevine (Vitis vinifera) proanthocyanidins contribute to plant defense mechanisms against biotic stress and also play a critical role in organoleptic properties of wine. In grapevine berry, these compounds are mainly accumulated in exocarps and seeds in the very early stages of development. A previous study has already identified VvMybPA1 as the first transcription factor involved in the regu...

Baobab (Adansonia digitata) fruit had received growing attention for its myriad nutritional and medicinal benefits, including those from polyphenol-rich profile powerful antioxidant activity. The current study evaluated the bioaccessibility of phenolic constituents capacity baobab pulp (BFP) byproduct, shell (BFS), upon in vitro digestion. In general, digestion reduced contents capacity; howeve...

Glutathione S-transferase (GST) plays an important role in the transport and accumulation of anthocyanin and proanthocyanidin in plants. In our previous study on Arabidopsis thaliana overexpressing the PRODUCTION OF ANTHOCYANIN PIGMENT 1 (PAP1) gene encoding an MYB transcription factor, the AtGSTF5 and AtGSTF6 genes encoding GST-like protein were up-regulated along with TRANSPARENT TESTA 19 (TT...

Lipopolysaccharide (LPS) is an important pathogenic factor for sepsis which results in cardiovascular diseases and even mortality. Proanthocyanidin, one of the main components grape seed, has a wide range biological activities various diseases. The mouse model was established by intraperitoneal injection with LPS. Grape seed proanthocyanidin (GSP) administered continuously 8 days. Our showed th...

We determined the phenolic, anthocyanin, and proanthocyanidin content of three brown, purple, and red rice brans isolated from different rice varieties using HPLC-PDA with the aid of 27 standards of known structure and matching unknown peaks to a spectral library of known compounds. Antioxidative capacities were determined by DPPH and ORAC and cell-inhibiting effects using an MTT assay. Based o...

Background and AimsHepatic ischemia-reperfusion injury (IRI) is a common pathophysiological phenomenon in clinical practice, which usually occurs liver transplantation, resection, severe trauma, hemorrhagic shock. Proanthocyanidin (PC), exerted from various plants with antioxidant, antitumor, antiaging activity, were administrated our study to investigate the underlying mechanism of its protect...

Golden buckwheat ( Fagopyrum dibotrys , also known as F. acutatum ) is a traditional edible herbal medicinal plant with large number of secondary metabolites and considered to be source therapeutic compounds. Different ecological environments have significant impact on their compound content effects. However, little about the interactions between soil physicochemical properties, rhizosphere, en...

There is emerging evidence suggesting that consumption of beverage and food rich in polyphenol may offer protective effects against various neurodegenerative, cardiovascular diseases and cancers. Proanthocyanidins (PACs) are one of the most abundant polyphenol in human diets, but also one of the least absorbed polyphenol mostly due to their size and structure complexity. PACs or condensed tanni...

Three anthocyanin regulatory genes of maize (Zea mays; Lc, B-Peru, and C1) were introduced into alfalfa (Medicago sativa) in a strategy designed to stimulate the flavonoid pathway and alter the composition of flavonoids produced in forage. Lc constructs included a full-length gene and a gene with a shortened 5'-untranslated region. Lc RNA was strongly expressed in Lc transgenic alfalfa foliage,...

The SARS-CoV-2 Omicron variant has spread rapidly and is considered the predominant in world, its main characteristic related to evade immunity from natural infection or vaccines, due multiple mutations spike protein. On other hand, medicinal plants have been used as alternatives therapies ameliorate some signs symptoms COVID-19, our previous work, cat’s claw (Uncaria tomentosa) stem bark studi...