Ocular prostheses have been used for centuries to restore patient confidence, psychosocial relationships and improve quality of life. Methodology producing accurate has improved with technological discoveries. Recently, hand painting ocular the go-to method creating life like prostheses. However, digital printing a print envelope around an acrylic prosthesis shown decrease treatment rehabilitat...

Abstract Purpose: Foxp3 T-regulatory (Treg) cells are key to immune homeostasis but the function of paired amphipathic helix protein, Sin3a, is unknown. Methods: We studied effects Sin3a deletion in Treg cells. Results: Sin3a−/− FoxP3Cre mice died from severe autoimmunity by 2–3 weeks birth. Mice had enlarged lymph nodes, inflammation lungs, skin, livers and kidneys autoantibodies islet cells, ...

One of the primary factors that impact the master production scheduling performance is demand fluctuation, which leads to frequently updated decisions, thereby causing instability. Consequently, global cost deteriorates, and productivity decreases. A reactive approach based on parametric mixed-integer programming is proposed that aims to provide a set of plans such that a compromise between pro...

one of the problems that sometimes occur in gas allocation optimization is instability phenomenon. this phenomenon reduces the oil production and damages downhole and surface facilities. different works have studied the stability and suggested some solutions to override it, but most of them (such as making the well intelligent) are very expensive and thus they are not applicable to many cases. ...