The levels of four serum proteins, assayed by a radial immunodiffusion technique, have been measured in healthy women who had been given either the oestrogen or progestogen component of a combined oral contraceptive preparation for three weeks. Raised alpha(2)-macroglobulin and transferrin levels were found after oestrogen treatment but albumin and IgG did not significantly alter. In the proges...

Coagulation studies were performed on haemophilic patients during a controlled trial of oral contraceptive therapy. Treatment with a combined oestrogen-progestogen preparation was associated with a significant rise in the factor VII-X complex. This change was not observed during treatment with progestogen alone. The highest levels of factor IX and fibrinogen and the lowest levels of factor X we...

IUD) is thought to act immediately by inhibiting sperm and ovum viability or preventing implantation.2 The LNG-IUS has a different contraceptive mechanism of action that relies on hormonal effects on the endometrium, cervical mucus and uterotubal transport, and thus has a delayed onset.2,3 This is the rationale for advising additional contraception for 7 days if a LNG-IUS is inserted after Day ...

There is increasing interest in the role of androgens in the treatment of women but little is known about their long-term safety. There are also very few studies on testosterone therapy and breast cancer risk. However, some observations support the concept that androgens may counteract the stimulatory effects of estrogen and progestogen in the mammary gland. Mammographic breast density and brea...

Effect of pre-synchronisation with progestogen and eCG on reproductive activity in synchronised ewes during anoestrous season | B Guner, R Kulaksiz, N Saat, I Kisadere, M Ozturkler, KY Dalginli, SM Pancarci Agricultural Journals

Objective To assess the thrombotic risk associated with oral contraceptive use with a focus on dose of oestrogen and type of progestogen of oral contraceptives available