prediction of the outcome and severity of acute upper gastrointestinal bleeding (ugib) has significant importance in patient care, disposition, and determining the need for emergent endoscopy. recent international recommendations endorse using scoring systems for management of non-variceal ugib patients. to date, different scoring systems have been developed for predicting the risk of 30-day mo...

background: the aim of the present study was to develop a scoring system for predicting 1-year major adverse cardiac events (mace), including mortality, target vessel or target lesion revascularization, coronary artery bypass graft surgery, and non-fatal myocardial infarction after percutaneous coronary intervention (pci). methods: the data were extracted from a single center pci registry. the ...

cell free dna (cfdna) is a genetic biomarker that is present in serum or plasma in high concentration in many types of cancer. identification of circu-lating cancer related dna molecules in serum or plasma is a non-invasive tool for early diagnosis and prognosis in many cancer patients. for this review, study selection and data extraction were performed by the authors. detection of point mutati...

conclusions the polymorphism and promoter methylation of rassf1a may be a significant factor in hcc, and can be an indicator for poor prognosis in patients with hcc. background the functional and prognostic significance of ras association domain family 1a gene (rassf1a) on hepatocellular carcinoma (hcc) has not been well characterized. objectives this study aimed to investigate the association ...

over half of all reported traumatic brain injuries are the result of a motor vehicle accident. other then the direct head impact itself, the sheer forces of the accident can cause the brain also to collide against the internal bone of the skull. in fact, when a moving head comes to a quick stop, the brain continues in its movement, striking the interior of the skull. this can cause bruising of ...

background: the natural history and etiology of malignant mesothelioma (mm) is already thoroughly described in the literature, but there is still debate on prognostic factors, and details of asbestos exposure and possible context with clinical and demographic data, have not been investigated comprehensively. objectives: description of patients with mm, focusing on exposure, occupation, survival...

Oral drugs stimulating endogenous insulin production (insulin secretagogues) may have detrimental effects on breast cancer outcomes. The data presented shows the relationship between pre-existing insulin secretagogues use, adipokine profiles at the time of breast cancer (BC) diagnosis and subsequent cancer outcomes in women diagnosed with BC and type 2 diabetes mellitus (T2DM). The Pearson corr...

the aim of this study was investigating the characteristic and outcome of self-immolation cases admitted to the burn centre of birjand, iran over an eight year period. this study is a retrospective review of case notes for patients with self-immolation and admitted to our referral burn centre in the last 8 years (january 2003-january 2011). a performa was designed to collect the data such as: d...

background: acute methanol poisoning is one of the most important chemical poisoning due to drinking of illegal and handmade alcoholic beverages in iran. the aim of this study was to evaluate clinical and biochemical parameters as prognostic factor in acute methanol poisoning. methods: a retrospective study was performed on acute methanol poisoning cases admitted to the loghman hakim hospital p...

today, the treatment of patellar luxations using current techniques has become a very common procedureas part of the surgical treatment. nevertheless, there are some doubts about such procedures in restraining the patella in lower grade cases. the purpose of the present retrospective clinical study was to determine theefficacy of the soft tissue and bone reconstructive procedures used for vario...