background and objective: male breast carcinoma (mbc) is an unusual form of neoplasia, representing 0.7 to 1 percent of all breast cancer cases. usually, the carcinoma affects patients after the sixth decade. the aim of this study was to evaluate the status of estrogen and progesterone receptors (er and pr) and prognostic factors (p53 and her-2/neu) in a series of male patients with breast canc...

conclusions the hormonal levels were low in patients with idiopathic dilated cardiomyopathy. however, the prognostic significance of different hormonal deficiencies was not clear in our study populations who were receiving standard therapies for heart failure and had a relatively stable clinical condition. results except for testosterone level, the levels of gh, igf-1, t3, and t4 concentrations...

hepatocellular carcinoma (hcc) is very rare during pregnancy and has a worse prognosis in pregnant women compared to those who are not pregnant. we present a case of hcc in a 41- year-old pregnant patient who was referred to our academic hospital. the patient presented with chief complaints of abdominal pain, jaundice, edema and hypertension. laboratory results were notable for elevated liver e...

objective epilepsy is a known condition in both children and adults but less evidence is available about the refractory epilepsy, the causes of treatment failure and the strategies to confront it. we intend to find the prognostic factors to detect the patients who will fail the treatment, in the early stages of the disease. materials & methods after defining the criteria for exclusion and exclu...

objective(s): the present study aimed to evaluate the role of pretherapeutic 18fluorine-fluorodeoxyglucose positron emission tomographycomputed tomography (18f-fdg pet-ct) and maximum standardized uptake value (suvmax) in guiding the treatment strategy and predicting the prognosis of esophageal carcinoma, using the survival data of thepatients.methods: the present retrospective, cohort study wa...

background and purpose: regarding usefulness of revascularization versus optimal medical therapy in patients with stable angina pectoris, data are challenging. the aim of this 12-month follow-up study was to compare the survival benefit associated with revascularization versus optimal medical therapy on the patients with stable angina pectoris. materials and methods: a prospective clinical stud...

background: status epilepticus (se) is one of the most common neurological emergencies with high mortality and morbidity. this study aims to determine the most common causes and outcomes of se in adult patients from fars province in southern iran. materials and methods: 134 patients with se (either convulsive or non-convulsive), admitted to namazi hospital, were enrolled from january 2006 to fe...

knowledge about the clinical significance of v-raf murine sarcoma viral oncogene homolog b1 ( braf ) mutations in colorectal cancer (crc) is growing. braf encodes a protein kinase involved with intracellular signaling and cell division. the gene product is a downstream effector of kirsten ras 1( kras ) within the ras/raf/mapk cellular signaling pathway. evidence suggests that braf mutations, li...

introduction: malaria is a protozoal disease, transmitted to humans by female anopheles mosquito bite. plasmodium falciparum, compared to other kinds of plasmodium, causes more severe malaria and is associated with a higher mortality rate. annually, one to three million deaths occur due to malaria, especially by p. falciparum. case presentation: in this report, we introduce an iranian patient s...

background: lactic acidosis in cardiac surgical patients is a manifestation of systemic inflammation and excess pro-inflammatory cytokine production. this investigation was designed to integrate basic concepts about lactate acidosis with a clinically used of serum lactate in patients under coronary artery bypass surgery (cabg) by on pump method. methods: from august to september 2012, 15 patien...