Although support for same-sex marriage has grown dramatically over the past decade, public opinion remains markedly divided. Here, we propose that the political divide over same-sex marriage represents a deeper divide between conflicting mating strategies. Specifically, we propose that opposition to same-sex marriage can be explained in terms of (a) individual differences in short-term mating o...

We report on the relation between various aspects of sexual activity and risk of infection with sexually transmitted disease (STD) in two groups of men attending an STD clinic. Sexual promiscuity appeared to have little effect on the distribution of most STDs, showing a strong association only with gonorrhoea. This finding was contrary to expectation but consistent with the results reported in ...

Review on enzyme promiscuity and opportunities for engineering http://www.weizmann.ac.il/Biological_Chemistry/scientist/ Tawfik/papers/(109)BarEven_CoOpBiot_2013.pdf This review article discusses a number of enzymes with broad specificity in the context of enzyme promiscuity. Soluble methane monooxygenase: KEGG database http://www.genome.jp/dbget-bin/ www_bget?ec:1.14.13.25 Soluble methane mono...

The ability of target proteins to bind structurally diverse compounds and compounds with different degrees of promiscuity (multi-target activity) was systematically assessed on the basis of currently available activity data and target annotations. Intuitive first- and second-order target promiscuity indices were introduced to quantify these binding characteristics and relate them to each other....

We study the relation between different social behaviors and the onset of epidemics in a model for the dynamics of sexual transmitted diseases. The model considers the society as a system of individual sexuated agents that can be organized in couples and interact with each other. The different social behaviors are incorporated assigning what we call a promiscuity value to each individual agent....

Combinatorial biosynthesis approaches that involve modular type I polyketide synthases (PKSs) are proven strategies for the synthesis of polyketides. In general however, such strategies are usually limited in scope and utility due to the restricted substrate specificity of polyketide biosynthetic machinery. Herein, a panel of chemo-enzymatically synthesized acyl-CoA's was used to probe the prom...