Complicated solution environments in oiling-out crystallization can lead to particle agglomeration with wide size distribution and low purity of the products, due complex interactions among two liquid phases one solid phase during crystallization. This research mainly focuses on optimization by controlling process a model system propyl paraben–ethanol–water. Nucleation control technologies, wet...

Particular attention are recently receiving antimicrobial agents added as preservatives in hygiene and cosmetics commercial products, since some of them are suspected to be harmful to the human health. The preservatives used belong to different classes of chemical species and are generally used in their mixtures. Multi-component methods able to simultaneously determinate species with different ...

Abstrak Kuffea merupakan produk lulur herbal tradisional yang terbuat dari tanaman berkhasiat obat yaitu bubuk daun kelor, kunyit, dan kopi. Formulasi bentuk krim 0,25 ml ekstrak 0,1 1 kopi, kulit 0,3 gram 7 tepung beras, tapioka, 2 butiran scrub, 5 asam stearat, 3 cetyl alkohol, 0,05 propyl paraben, 50 aquades, 6 propylen glikol, metyl parfum. 0,5 16 8 scrub. Proses pembuatan “Kuffea” ekstrak,...

OBJECTIVE We previously demonstrated that exposure to polyvinyl chloride plastic medical devices containing di(2-ethylhexyl) phthalate (DEHP) was associated with higher urinary concentrations of several DEHP metabolites in 54 premature infants in two neonatal intensive care units than in the general population. For 42 of these infants, we evaluated urinary concentrations of several phenols, inc...

Antioxidative effect of aqueous extract of rhizome of Ginger (Zinziber officinale) was examined on p-hydroxybenzoic acid (paraben) induced lipid peroxidation. Addition of paraben (25-150 microg/mL) to liver and kidney homogenates significantly increases H2O2 induced lipid peroxidation in vitro. Effect was dose dependent up to 100 microg/mL concentration. An addition of aqueous extract of ginger...

In recent years, paraoxybenzoic acid esters (parabens) have been used in pharmaceuticals, cosmetics, and food additives. Parabens reported to a weak estrogenic effect vitro test systems, it is presumed that the longer alkyl chain of paraben, greater its endocrine-disrupting reproductive function effects. However, effects parabens on human health are still unclear. this study, we evaluated six (...

Makasar fruit (Brucea javanica [L]. Merr) has been widely used as herbal medicine to treat various types of diseases through simple processing. However, the use drugs with topical application an ointment incision wounds or diabetic is extremely rare. The purpose this research produce and assess physical quality made from ethanolic extract Makassar fruit. in study was ethanol fruit, alpha tocoph...

Ovarian cancer is one of the major causes of death in women. Parabens are a class of chemicals widely used as preservatives in cosmetic and pharmaceutical products, they mimic estrogens, which are known to play a role in the development of different cancers in women. The Aim of this study was to investigate the proliferative effects of Methyl Paraben (MP) and Propyl Paraben (PP) on human ovaria...

Antibiotics are not chemically stable in water based oral pharmaceutical suspensions. Anhydrous liquid antibiotic suspension for oral administration provides a product having good shelf life and taste characteristics relative to conventional liquid formulations. A ready to use oil based cefpodoxime proxetil preparation which can be stored at room temperature was prepared and evaluated for its o...

Many children become HIV+ due to mother-to-child transmission, a risk that can be largely eliminated if infants ingest antiretroviral (ARV) medications immediately after birth. As most mothers in Africa deliver at home, the ARV must be provided at their last antenatal visit, sometimes months before birth. No current drug delivery system allows the mother to store the medication at home long eno...