Benign prostatic hyperplasia (BPH; Pic. 1) is characterized by increased size of the prostate leading to difficulties with passing the urine. The cells of prostate may increase in numbers (hyperplasia) or in size (hypertrophy) resulting in larger size of prostate. As result, prostatic nodules form in the transition zone of the prostate, which is the area where the prostate is surrounding the ur...

background transurethral resection of the prostate (turp) is the most common surgical treatment for benign prostatic hyperplasia. objectives the aim of the present study was to compare the conventional bipolar transurethral resection of prostate (turp) with a modified transurethral resection of the prostate (m-turp) in men with mild to moderate symptoms of benign prostatic hyperplasia. patients...

Hajime Sugiura and Susumu Hasegawa Department of Urology, Nagoya City University Medical School (Director: Prof. N. Oka) Since our original report of transrectal approach using television fluoloscopy for roentgenographic visualization of benign prostatic hyperplasia, we have continued to apply this technique to the cases of benign hyperplasia, carcinoma, inflammatory disease and normal conditio...

Introduction: Benign Hyperplasia of the Prostate (BHP) and prostate cancer comprise about 90% all diseases gland. An increase in serum Specific Antigen (PSA) is an indicator underlying hyperplasia, inflammation, or cancer. Mast cells are found both inflamed tumour tissue. Aim: To find correlation mast cell count with age, weight prostate, PSA level, thereby distinguishing between benign inflamm...

OBJECTIVE The objective of this study was to investigate the expression of telomere repeat binding factor 1 (TRF1) and TRF2 in prostate cancer and their relationships with clinicopathological features. METHODS In total 50 prostate cancer tissues and paired benign prostate hyperplasia tissues were analyzed. The telomere-binding proteins TRF1 and TRF2 were measured using immunohistochemical met...

Benign prostatic hyperplasia refers to the non-malignant growth or enlargement of prostate gland and is a general cause lower urinary tract symptoms in men which rises with growing age. There wide range management options available from watchful waiting, medicinal therapy various surgical intervention methods. Though preliminary treatment for benign hyperplasia, some patients lack desire keep o...

PURPOSE The incidence of benign prostatic hyperplasia increases among obese individuals, but few studies have fully explained the underlying mechanisms. Adiponectin has drawn much attention in recent years due to its protective role in obesity-related diseases. Here we aimed to investigate the possible molecular mechanisms and clinical significance of adiponectin in relation to benign prostatic...

Background: Prostate cancer is the second form of cancer among men worldwide. For early cancer detection, we should identify tumors in initial stages before the physical signs become visible. The present study aims to evaluate the diagnostic value of cell-free DNA (cfDNA), its comparison with prostate-specific antigen (PSA) level in prostate cancer screening and also in patients with localized ...

Introduction: Estrogen Receptor 1 (ESR1) expression has appeared to impact prostate cancer advancement significantly. This study aims compare the of ESR-1 in BPH and cancer. Methods: The samples were collected from a single-center hospital 2014 2020. We exclude which RNA concentration is under minimum standard allowance proceed. Deparaffinize formalin-fixed paraffin-embedded RNAs extraction by ...

Introduction: Prostate cancer is the second common malignancy in men. Prostatic intraepithelial neoplasia (PIN) precursor lesion of prostatic carcinoma. Histopathological examination necessary to diagnose PIN lesions. Objective: The aim study determine incidence and analyse usefulness basal cell marker p63 expression various lesions prostate. Methods: This a two-year prospective 65 transurethra...