Background: Benign prostatic hyperplasia (BPH) is the most common benign tumor in men. The etiology of BPH is still unresolved and multiple systems are likely to be involved. The effects of diabetes on urinary system are a risk factor for BPH. We then assessed the effects of diabetes on the parameters related to BPH, especially weight and volume. Methods: This study was conducted on patients...

Background and Objective: Prostate cancer is a prevalent disease around the world. The prostatic specific Antigen (PSA) test has recently proved itself as a useful method for the diagnosis and examination of patients with prostatic cancer. The objective of this study was to compare the stability of free PSA and total PSA in different storage settings. Materials and Method...

Gold nanowires functionalized for electrochemical immunosensing were prepared and demonstrated to detect prostate specific antigen (PSA) with the sensitivity required in molecular and clinical diagnostics.

OBJECTIVES To explore the attitudes of men with confirmed or suspected prostate cancer to testing for prostate specific antigen. DESIGN Qualitative interview study with a purposive sample. SETTING Great Britain. PARTICIPANTS 52 men with suspected or confirmed prostate cancer, recruited through general practitioners, urologists, patient support groups, and charities. RESULTS Almost all m...

BACKGROUND Prostate-specific antigen (PSA) assays have historically produced different results. Our aim was to investigate the comparability of assay results of selected commercially available assay methods designed to measure total, free, or complexed PSA (tPSA, fPSA, and cPSA). METHODS We measured tPSA, fPSA, and cPSA in 70 samples and in the WHO PSA 96/670 reference preparation with 6 assa...

PURPOSE We tested the hypothesis that serum isoform [-2]proPSA derivatives %p2PSA and Prostate Health Index are accurate predictors of prostate cancer in men scheduled for repeat biopsy. MATERIALS AND METHODS The study was an observational prospective evaluation of a clinical cohort of men with 1 or 2 previous negative prostate biopsies, with persistent suspicion of prostate cancer. They were...