MOTIVATION In general, most accurate gene/protein annotations are provided by curators. Despite having lesser evidence strengths, it is inevitable to use computational methods for fast and a priori discovery of protein function annotations. This paper considers the problem of assigning Gene Ontology (GO) annotations to partially annotated or newly discovered proteins. RESULTS We present a dat...

We produced a set of pseudoisochromatic plates for determining individual color-difference thresholds to assess test performance and test properties, and analyzed the results. We report a high test validity and classification ability for the deficiency type and severity level [comparable to that of the fourth edition of the Hardy-Rand-Rittler (HRR) test]. We discuss changes of the acceptable ch...

We have developed 3 series of pseudoisochromatic plates for colour vision testing. The plates are arranged in order of increasing difficulty. In the first (red/green) series, a red Landolt C is shown in front of a green background. This series is used to determine the severity of colour vision deficiency. In the second series, colours are located on the protan confusion line, whereas in the thi...

The influence of congenital colour defects on a clinical computer test for equiluminous colour discrimination is studied. Differences in relative spectral sensitivity and changes in colour contrast discrimination are two distinct manifestations of the abnormal genes responsible for congenital red-green defects. The very simple and rapid method of the heterochromatic flicker brightness test acts...

The congenital color vision deficient (CVD) generally demonstrates difficulties in color naming tasks. In our study we investigated color naming properties and uncertainties of a relatively large group of red-green CVDs using quasi monochromatic stimuli and seven basic color terms. The results show a large variability in color naming for the CVD when contrasted to normal color vision and simila...

Five thousand one hundred and twenty-nine Wisconsin children, ages 4–12 years, were tested for colorvision deficiencies using a newly devised, precisely calibrated paper-and-pencil test. The disposable 1-page test consisted of 1 demonstration and 8 test panels. Thousands of copies of the test were produced, and they were distributed and administered in classrooms by teachers. Children wrote dir...