The amount and conformation of bovine serum albumin upon adsorption on titanium (Ti) surfaces containing nanotubes with different pore sizes were investigated. Nanotubes created the via anodization. Protein behavior anodized compared smooth sanded Ti surfaces. conformational changes in surface adsorbed proteins evaluated using second derivative curve fitting methods applied to Fourier transform...

Protein aggregation is phenomenon wherein protein loses its native structure and aggregates due to the adaption of non-native conformation. Amyloid aggregation formed by the accumulation of various proteins causes many diseases in humans and other organisms. Antioxidants can prevent proteins aggregation. Pulicaria undulata  extract along with phenolic compounds can increase protein stability an...

The average lifespan of artificial joints is 15–25 years, but it still too short for young and active patients. Human synovial albumin easily adsorbed on the surfaces joint materials has increased friction when subjected to conformational changes. Most studies have focused interaction between fluid components protein conformation not been modified, how reduce wear caused by denatured proteins. ...

Abstract Coronaviruses of bats and pangolins have been implicated in the origin evolution pandemic SARS-CoV-2. We show that spikes from Guangdong Pangolin-CoVs, closely related to SARS-CoV-2, bind strongly human pangolin ACE2 receptors. also report cryo-EM structure a Pangolin-CoV spike protein it adopts fully-closed conformation that, aside Receptor-Binding Domain, resembles bat coronavirus Ra...