INTRODUCTION Proteinuria is a common marker of kidney damage. This study aimed at determining predictors of proteinuria in subjects without impaired renal filtration function in Owerri, Nigeria. METHODS This was a cross-sectional study involving 136 subjects, consecutively drawn from Federal Medical Centre (FMC), Owerri, Nigeria. Relevant investigations were performed, including 24-hour urine...

OBJECTIVE To determine the diagnostic accuracy of two "spot urine" tests for significant proteinuria or adverse pregnancy outcome in pregnant women with suspected pre-eclampsia. DESIGN Systematic review and meta-analysis. DATA SOURCES Searches of electronic databases 1980 to January 2011, reference list checking, hand searching of journals, and contact with experts. INCLUSION CRITERIA Dia...

Diabetes mellitus is the commonest cause of ESRD worldwide and third most common cause in Nigeria. Recent reports from Nigeria indicate the prevalence of diabetic nephropathy as an aetiology of ESRD is increasing necessitating early diagnosis of diabetic nephropathy. We measured the urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG), NAG/creatinine ratio, urinary protein-creatinine rati...

Background and Objective: Preeclampsia (PE) is a pregnancy complication with the signs of kidney damage. The effect of S-Allyl-cysteine (SAC) on inflammatory cytokines was evaluated to prevent PE-induced renal complications. Materials and Methods: Wistar rats were divided into seven groups: 1) control, 2) PE, 3) EC, 4) PE+SAC50, 5) PE+SAC200, 6) EC+SAC50, and 7) EC+SAC200. In Groups 1-3, the r...

This is the second of two articles that together aim to explore current understanding of the clinical value of measuring serum/plasma urea concentration. The main focus of the first article [1] was physiological topics, such as urea production and renal processing of urea. The causes of increased and reduced plasma/serum urea concentration were also discussed. The main focus of this second arti...

background:the first step in diagnosis of diabetic nephropathy is measurement ofalbumin in a spot urine sample. the aim of this study was assessment of the accuracy of urinary albumin to creatinine ratio (uacr) in random urine specimens (rus) for microalbuminuria and macroalbuminuria screening in iranian diabetic patients. methods:a total of 200 diabetic patients participated to our study. 24 h...

Present study was undertaken during a period of 6 months (September 2008-February 2009) to see an correlation of 24 hours urine protein estimation with random spot protein-creatinine (P:C) ratio among a diabetic patients. The study comprised of 144 patients aged 30-70 years, recruited from Kantipur hospital, Kathmandu. The 24-hr urine sample was collected, followed by spot random urine sample. ...