The use of proteins as biological tools and therapeutic agents is limited due to the fact that proteins do not effectively cross the plasma membrane of cells. Here, we report a novel class of protein transporter molecules based on protein transduction domain mimics (PTDMs) synthesized via ring opening metathesis polymerization (ROMP). The PTDMs reported here were specifically inspired by amphip...

Boronate Building Blocks building blocks have been developed for intracellular protein delivery. Article 2202049 by Qianyi Ren, Yiyun Cheng, and Jia Lv provides a summary of boronate chemistry used in the design cytosolic delivery systems. The can address barriers existing process.