rotavirus, a triple-layered non-enveloped member of the reoviridae family, obtained a transient membrane envelope when newly synthesized subviral particles bud into the endoplasmic reticulum (er). as rotavirus particles mature, they lose their transient membrane and obtain outer layer. it is mostly believed that only double layered particles bud into the er. the present study describes that the...

Determination of protein subcellular localization plays an important role in understanding protein function [1]. Knowledge of subcellular localization is also essential for genome annotation and drug discovery. Moreover, abnormal subcellular localization has been correlated with several diseases, such as cancer and Alzheimer’s disease. Experimental determination of protein subcellular localizat...

Leukotriene B4 receptor type 2 (BLT2) is a G protein-coupled (GPCR) mainly expressed in epithelial cells, where it enhances barrier function. A unique characteristic of BLT2 its restricted localization to the lateral membrane. However, molecular mechanism underlying membrane and physiological roles laterally localized are unknown. BLT1 most homologous GPCR localizes both apical membranes. In th...

Protein subcellular localization is a major determinant of protein function. However, this important protein feature is often described in terms of discrete and qualitative categories of subcellular compartments, and therefore it has limited applications in quantitative protein function analyses. Here, we present Protein Localization Analysis and Search Tools (PLAST), an automated analysis fram...

objectives: the aim of the present study was to assess the auditory lateralization ability in children with (central) auditory processing disorder. methods: participants were divided in two groups: 15 children with central auditory processing disorder (8-10 years) and 80 normal children (8-11 years) from both genders with pure-tone air-conduction thresholds better than 20 db hl bilaterally and ...

a wireless sensor network (wsn) is a wireless decentralized structure network consists of many nodes. nodes can be fixed or mobile. wsn applications typically observe some physical phenomenon through sampling of the environment so determine the location of events is an important issue in wsn. wireless localization used to determine the position of nodes. the precise localization in wsns is a co...

The site of oskar RNA and protein localization within the oocyte determines where in the embryo primordial germ cells form and where the abdomen develops. Initiation of oskar RNA localization requires the activity of several genes. We show that ovaries mutant for any of these genes lack Oskar protein. Using various transgenic constructs we have determined that sequences required for oskar RNA l...

in wireless sensor networks (wsns), localization algorithms could be range-based or range-free. the approximate point in triangle (apit) is a range-free approach. we propose modification of the apit algorithm and refer as modified-apit. we select suitable triangles with appropriate distance between anchors to reduce pit test errors (edge effect and non-uniform placement of neighbours) in apit a...