We conducted a study to identify circular RNAs associated with invasive non-functioning pituitary adenomas and chemoresistance, as well construct competitive endogenous RNA network. performed expression profiling of 10 specimens using sequencing identified 37 differentially expressed RNAs, which were validated real-time quantitative polymerase chain reaction. also detected 26 microRNAs 388 mess...

A method is described for the detection of protein tyrosine phosphatase activity in sodium dodecyl sulfate-polyacrylamide gels. A radiolabeled substrate, 32P-labeled poly(glutamic acid-tyrosine) (random copolymer) is incorporated into gels prior to polymerization. Following electrophoresis, the sodium dodecyl sulfate is removed; the proteins are fully denatured by soaking gels in 6 M guanidine ...

Submit Manuscript | http://medcraveonline.com Abbreviations: T1D: Type 1 diabetes; T2D: Type 2 diabetes; NIDDM: Non-Insulin-Dependent Diabetes Mellitus; TNF-α: Tumor Necrosis Factor Alpha; IRS: Insulin Receptor and Substrates; RXR: Retinoid X-Receptor; PTP1B: Protein Tyrosine Phosphatase 1B; PTPs: Protein Tyrosine Phosphatases; GPR: G-Protein Coupled Receptor; LA: Lipoic Acid; NAC: N-Acetyl-l-C...