Echinococcus granulosus, the etiologic agent of cystic echinococcosis (CE) in humans and other animal species, is distributed worldwide. Ten intra-specific variants, or genotypes (G1-G10), have been defined based on genetic diversity. To determine the genotypes present in endemic areas of Peru, samples were collected from cattle (44), sheep (41) and humans (14) from Junín, Puno Huancavelica, Cu...

Alternative splicing (AS), as one of the most important topics in the post-genomic era, has been extensively studied in numerous organisms. However, little is known about the prevalence and characteristics of AS in Echinococcus species, which can cause significant health problems to humans and domestic animals. Based on high-throughput RNA-sequencing data, we performed a genome-wide survey of A...

CASE REPORT A 49-year-old female noticed a deep-seated nodule with rubbery consistency on right upper arm for 2 months. Erythematous change on surface was seen (Fig. 1). She was suffered from mild itching sensation without pain or tenderness. The lesion progressed in size gradually. She visited our hospital for help and excisional biopsy was performed. Histologically, a well-defi ned nodule cir...

BACKGROUND Heavy-ion therapy has an advantage over conventional radiotherapy due to its superb biological effectiveness and dose conformity in cancer therapy. It could be a potential alternate approach for hydatid cyst treatment. However, there is no information currently available on the cellular and molecular basis for heavy-ion irradiation induced cell death in cystic echinococcosis. METHO...

The present study was designed to investigate the cross-protection (protective immunity) between Hydatid cyst and Bladder worm evaluate immunologic response of both humerol cellular immunity in mice. To achieve these goals, 120 mice were used equally divided into four groups immunized subcutaneously with 2 doses antigen at first 14 days experiment. Mice group (n=30) 0.3 ml hydatid sonicated pro...

in this study, the immunogenicity of three types of antigens (hydatid fluid, protoscolices and whole body of e. granulosus) was investigated in lambs by elisa. sixteen 4–6-month-old lambs of mixed sexes were divided into 4 groups of 4 lambs (three immunized and one control group). twelve lambs as immunized groups received 2 mg of hydatid fluid, protoscolices and whole body of e. granulosus ant...

in current study, a few sheep cystic livers and lungs were obtained from mashhad slaughter house and protoscolex were separated aseptically. thirty 6-week-old swiss mice were divided into 5 groups and two thousands of live protoscolices were inoculated intrapritoaneally in each mouse. in group 1 and 2 (prophylactic groups), mice were given 150 mg/kg of oral albendazole and mebendazole for 10 da...