Department of Paediatric Urology, University College London Hospitals NHS Foundation Trust, London, UK Department of Paediatric Urology, Great Ormond Street Children Hospital NHS Trust, London, UK Department of Paediatric Surgery, The Royal Belfast Hospital for Sick Children, Belfast, UK Department of Neonatology, The Royal Belfast Hospital for Sick Children, Belfast, UK Department of Paediatri...

Similar to phrase-based machine translation, hierarchical systems produce a large proportion of phrases, most of which are supposedly junk and useless for the actual translation. For the hierarchical case, however, the amount of extracted rules is an order of magnitude bigger. In this paper, we investigate several soft constraints in the extraction of hierarchical phrases and whether these help...

Compartmentalized cAMP signaling regulates mitochondrial dynamics, morphology, and oxidative phosphorylation. However, regulators of the mitochondrial cAMP pathway, and its broad impact on organelle function, remain to be explored. Here, we report that Drosophila Prune is a cyclic nucleotide phosphodiesterase that localizes to the mitochondrial matrix. Knocking down prune in cultured cells redu...

In this paper, we give a (polynomial-time) 3-approximation algorithm for the rooted subtree prune and regraft distance between two phylogenetic trees. This problem is known to be NP-complete and the best previously known approximation algorithm is a 5-approximation. We also give a faster fixed-parameter algorithm for the rooted subtree prune and regraft distance than was previously known.

Recent years have seen an increasing emphasis on developing more precise accounting measures of marketand customer-level profitability. These efforts are aimed at helping prune unprofitable constituencies and targeting resources to more profitable segments. This paper demonstrates that even if perfected, such refined segment profitability measures may unwittingly neglect a latent cross-subsidiz...

Model pruning seeks to induce sparsity in a deep neural network’s various connection matrices, thereby reducing the number of nonzero-valued parameters in the model. Recent reports (Han et al., 2015a; Narang et al., 2017) prune deep networks at the cost of only a marginal loss in accuracy and achieve a sizable reduction in model size. This hints at the possibility that the baseline models in th...