BACKGROUND The relationship between the duration of untreated psychosis and long-term clinical outcomes remains uncertain. OBJECTIVE Prospectively assess the relationship of the duration of untreated psychosis on clinical outcomes in a sample of individuals with first-onset schizophrenia treated at the Pudong Mental Health Center from January 2007 to December 2008. METHODS Information about...

There are clearly documented evidence concerning violence by the mentally ill. The violence may be committed on the basis of delusional beliefs or exacerbation of symptomatology. Family members have been the object of violence in more than 50% of the cases.It is not surprising, therefore, that patients are brought restrained to the psychiatric treatment units. This study was thus conducted to f...

BACKGROUND There is concern over the methods used to evaluate antipsychotic drugs. AIMS To assess the clinical relevance of findings in the literature. METHOD A systematic review identified studies of antipsychotics that used the Brief Psychiatric Rating Scale (BPRS) and Positive and Negative Syndrome Scale (PANSS). A published method of translating these into Clinical Global Impression - C...

INTRODUCTION There has been a relative lack of research on deaf people with schizophrenia, and no data exist regarding symptom structure in this population. Thus, we determined the factor structure of the 24-item Brief Psychiatric Rating Scale (BPRS) in deaf (n = 34) and hearing (n = 31) people with schizophrenia and compared it to a standard four-factor solution. METHOD An obliquely rotated ...

Sir, We read with interest the study by Payee et al. (1999). Authors remark that no study on the treatment of catatonia with lorazepam has been carried out in India. In this context, we would like to mention that a similar but more exhaustive study has been conducted by us on a larger patient population at Central Institute of Psychiatry, Ranchi. We share a few findings from our study, which is...

Only few studies have compared the psychopathological features in first episode psychosis (FEP) and chronic schizophrenia (CS) patients. The aim of our study was to compare sociodemographic and clinical aspects of FEP and CS inpatients using the Positive and Negative Syndrome Scale (PANSS) and the Brief Psychiatric Rating Scale (BPRS) in order to better characterize FEP. We did not find signifi...

BACKGROUND Despite the widespread use of the Brief Psychiatric Rating Scale (BPRS), the clinical meaning of its total score and cut-off values used to define treatment response are unclear. AIMS To link the BPRS to Clinical Global Impression (CGI) ratings. METHOD Equipercentile linking of BPRS and CGI ratings from seven drug trials in acutely ill patients with schizophrenia (n=1979). RESU...

PURPOSE The aim of this study was to investigate the correlation between changes in symptoms and changes in self-reported quality of life among Chinese patients with schizophrenia who were switched from a typical antipsychotic to olanzapine during usual outpatient care. PATIENTS AND METHODS This post hoc analysis was conducted using data from the Chinese subgroup (n=475) of a multicountry, 12...

OBJECTIVE In this cross-sectional study, we sought to assess the extent of internalized stigma among inpatients and outpatients with schizophrenia in the People's Republic of China and to investigate whether education level correlated with the experience of stigma. METHODS Schizophrenia patients were evaluated using the Brief Psychiatric Rating Scale (BPRS), the Positive and Negative Syndrome...

OBJECTIVE To determine whether or not risperidone is efficacious in treating self-induced water intoxication in patients with chronic schizophrenia. METHOD We carried out a prospective 11-month open-label study using risperidone to treat 8 men with chronic schizophrenia and self-induced water intoxication. RESULTS The 8 men were not able to reduce their fluid consumption compared with their...