Background Acute generalised exanthematous pustulosis (AGEP) also known as pustular drug eruption is an unusual drug induced hypersensitivity skin manifestation, characterized by acute onset of fever, and numerous non-follicular pinhead sterile pustules on erythematous background , usually over the flexural areas and face [1]. Neutrophils are involved in the pathogenesis of AGEP. Neutrophilacti...

Acrodermatitis continua of Hallopeau (ACH) is an uncommon inflammatory disease manifesting as sterile pustular eruption of the fingers and toes. The disease is of a chronic relapsing nature and is often refractory to treatment. With longstanding disease, osteitis with consequent bone resorption of the underlying phalanges can occur, leading to disability. While the incidence of ACH is rare in c...

Subcorneal pustular dermatosis (SPD), is rare, chronic, and relapsing pustuler eruption. Mostly, it affects middle-aged elderly women. Mucosal involvement extremely rare. Here we report a 31-year-old woman with generalized SPD lip involvement. The patient had annular or serpiginous patterned well-demarcated plaques on the trunk, intertriginous areas flexor aspects of limbs, palmoplantar areas, ...

Nodular granulomatous perifolliculitis is a well-recognized infection of the dermal and subcutaneous tissue caused by dermatophytes, which normally do not invade beyond the epidermis. We report here one such case that occurred in an immunosuppressed individual. The patient was a 35-year-old farmer who presented with small pruritic eruption that had initially appeared on the lower leg and then h...

INTRODUCTION We describe a patient who developed an acute generalised pustular eruption associated with pyrexia at 33 weeks of gestation. CLINICAL PICTURE Her condition was complicated by preterm labour, requiring an emergency caesarean section delivery. A diagnosis of impetigo herpetiformis was made on clinicopathological grounds. TREATMENT Initial treatment with topical and systemic corti...

weak response after 10 days of ciclosporin and the immediate need to control the systemic disease. After 4 weeks, the patient was free of pustules but a slight erythema was still present. At week 14, the patient was free of lesions, and, after the 5th infusion, she requested the suspension of infliximab. Efa lizumab was reintroduced with the maintenance of the excellent results (PASI-100) until...

CASE REPORT A 26-year-old woman of Vietnamese descent presented to the emergency department with a widespread, symmetric, erythematous, and pustular eruption (Fig 1). The outbreak initially affected the waistline, and the axillary, inguinal, and inframammary folds. It then spread to involve the neck, wrists, areolae, and the antecubital and popliteal fossae (Fig 2). The pustules were superficia...

Intraepidermal IgA pustulosis IgA paraproteinemia HIV infection Dr. José M de Moragas, Department of Dermatology, Hospital de la Sta. Creu i St. Pau, C/St. Antoni M Claret, 167, E-08025 Barcelona (Spain) Intraepidermal IgA pustulosis (IEAP) is a term coined by Wallach [1] characterized by a pustular eruption similar to the subcorneal pustulosis of Sneddon and Wilkinson, but it differs from this...