Abstract A group of transition‐metal catalyzed hydrogen moving reactions , encompassing autotransfer (HAT; also called borrowing BH), dehydrogenative condensation (DHC) and alkene isomerization, displays high atom economy relies on widely available starting materials. Such have considerable potential for clean reaction design application in sustainable synthesis. With the aim to develop study s...

Pyridine-C-nucleosides, „Inverse“ [4+2] Cycloadditions, 1,2,4-Triazine-C-nucleosides, 2,,3’-Dideoxy-/?-D-ribofuranosyl-pyridines The anomeric imido esters 5 and 6, appropriate precursors for C-nucleoside synthesis, were prepared and utilized as heterodienophiles in a Diels-Alder reaction with inverse electron demand to yield the novel, protected 1.2.4-triazine C-nucleosides 8 and 9. They could ...

Although azides have been widely used in nitrene transfer reactions, in situ generation of N-H imines from azides for downstream transformations has rarely been explored. We report copper-mediated formation of N-unsubstituted aliphatic imines from easily available aliphatic azides using a customized phenanthroline-based ligand (L1*). Through trapping in situ-generated N-H imines, multisubstitut...

MALWINA LLEN and JOHN D. ROBERTS. Can. J. Chem. 59,451 (1981). The effects of hydrogen bonding and protonation produced by changing solvent from chloroform to 2,2,2-trifluoroethanol to trifluoroacetic acid were determined for the 13C chemical shifts of fourteen imines, four oximes, and two pyridines. Downfield shifts relative to chloroform were observed for the C=N carbon of the imines and oxim...

The anion-radical coupling of structurally diverse series of aromatic compounds possessing biaryl linkages led to seven fused, polycyclic heterocycles in reasonable yields. The yield of the key step (K, toluene, O2) depends on both electronic and steric factors. The whole strategy consists of just two steps starting from an unsubstituted imidazo[1,2-a]pyridine, giving target compounds in an ove...

UNLABELLED BACKGROUND Imidazo[1,2-a]pyridines and pyrimidines are important organic fluorophores which have been investigated as biomarkers and photochemical sensors. The effect on the luminescent property by substituents in the heterocycle and phenyl rings, have been studied as well. In this investigation, series of 3-hydroxymethyl imidazo[1,2-a]pyridines and pyrimidines were synthesized an...

Periodic mesoporous organosilica with densely packed pyridine units within the framework and crystal-like molecular-scale periodicity was synthesized. The framework pyridines were chemically active and fully accessible for protonation and Cu(2+) adsorption.

Treatment of pyridines, quinoline and methylthiopyrazine with the frustrated Lewis pair TMPMgCl·BF(3) (1) leads to organotrifluoro borates which react readily with a variety of aromatic aldehydes in the absence of a transition metal catalyst.

Polar, noncentrosymmetric packing of directional, 1-D hydrogen-bonded networks of chiral, 4-amino-2,6-bis(oxazolinyl)pyridines (ampybox) occurs for isopropyl-substituted ampybox; in contrast, 1-D networks of methyl-substituted ampybox pack in an antiparallel arrangement.

The novel palladium-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid with aryl and heteroaryl bromides including benzenes, naphthalenes, pyridines and quinolines for C-C bond formation have been successfully achieved.