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of the Dissertation Fast and Robust Algorithms for Compressive Sensing and Other Applications

Many bacteria use small diffusible signalling molecules called Autoinducers to communicate each other termed as Quorum Sensing. The signalling molecules in grampositive bacteria are oligopeptides, in gramnegative bacteria are Nacyl homoserine lactone and a family of auto inducers known as auto inducer2 in both grampositive and gramnegative bacteria. These molecules are internalized in the cell ...

Biofilms are microorganisms, where bacteria are embedded in networks formed by bacteria-produced expopolysacharrides, also known as extracellular polymeric substances (EPS). Bacteria in biofilms communicate and cooperate with each other by sensing the density of signalling molecules that bacteria excrete. This phenomenon is known as quorum sensing (QS). In this paper, we develop a hydrodynamic ...

Anaerobic growth of Pseudomonas aeruginosa PAO1 was affected by quorum sensing. Deletion of genes that produce N-acyl-l-homoserine lactone signals resulted in an increase in denitrification activity, which was repressed by exogenous signal molecules. The effect of the las quorum-sensing system was dependent on the rhl quorum-sensing system in regulating denitrification.

Aeromonas hydrophila strain KOR1, isolated from mangrove rhizosphere soil, has the ability to produce the quorum-sensing signal molecule. Here, we report the 4.78-Mb genome sequence of strain KOR1, and found its quorum-sensing encoding gene LuxR. The data will be crucial to understanding the quorum-sensing-dependent phenotypes of this bacterium.

AIM This review intends to provide a brief overview regarding quorum sensing among bacteria in biofilms and also attempts to throw light on the new research focusing on interference with the quorum sensing. BACKGROUND Dental plaque is an example of microbial biofilm leading to periodontal disease and dental caries. Quorum sensing is widely employed by a variety of gram-positive and gram-negat...

In the Vibrio cholerae pathogen, initiation of bacterial quorum sensing pathways serves to suppress virulence. We describe herein a potent and chemically stable small molecule agonist of V. cholerae quorum sensing, which was identified through rational drug design based on the native quorum sensing signal. This novel agonist may serve as a useful lead compound for the control of virulence in V....

A number of bacteria, including some significant pathogens, utilize N-acylhomoserine lactones (AHLs) as quorum sensing signals. There is considerable interest in the therapeutic potential of disrupting quorum sensing. Recently, a number of bacteria have been identified which are capable of enzymic inactivation of AHLs. These enzymes show considerable promise as 'quenchers' of quorum sensing. Ho...