CAPSULE Background: DDI2 and DDI3 are two uncharacterized identical genes found in budding yeast. Results: They encode novel cyanamide hydratases and are massively induced by cyanamide. Their deletion causes cellular sensitivity to cyanamide. Conclusion: The two genes function in cyanamide detoxification and are tightly regulated. Significance: This is the first attempt to understand the duplic...
