نتایج جستجو برای: r58 j30 h71

تعداد نتایج: 354  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Raajit Rampal Jihae Ahn Omar Abdel-Wahab Michelle Nahas Kai Wang Doron Lipson Geoff A Otto Roman Yelensky Todd Hricik Anna Sophia McKenney Gabriela Chiosis Young Rock Chung Suveg Pandey Marcel R M van den Brink Scott A Armstrong Ahmet Dogan Andrew Intlekofer Taghi Manshouri Christopher Y Park Srdan Verstovsek Franck Rapaport Philip J Stephens Vincent A Miller Ross L Levine

Patients with myeloproliferative neoplasms (MPNs) are at significant, cumulative risk of leukemic transformation to acute myeloid leukemia (AML), which is associated with adverse clinical outcome and resistance to standard AML therapies. We performed genomic profiling of post-MPN AML samples; these studies demonstrate somatic tumor protein 53 (TP53) mutations are common in JAK2V617F-mutant, pos...

Journal: :Progrès en Urologie - FMC 2022

Seul 1,9 % des prostatectomies radicales (PR) sont réalisée en ambulatoire France 2020. Des données supplémentaires nécessaires pour confirmer la sécurité de cette pratique. Aucune étude n’explore satisfaction du patient dans PR manière comparative. Nous posons donc l’hypothèse que prostatectomie ou hospitalisation conventionnelle est équivalente terme complication, résultats oncologiques et pa...

2002
K. R. Khusnutdinova

We consider a system of coupled Klein-Gordon equations, which models one-dimensional nonlinear wave processes in two-component media. We find both linear and nonlinear solutions involving the exchange of energy between the different components of the system. The solutions are a continuum generalization of the classical example of energy exchange in Mandelshtam’s system of coupled pendulums. PAC...

2013
Robert Breunig Xiaodong Gong

We show that measurement error in the constructed price of child care can explain why previous Australian studies have found partnered women’s labour supply to be unresponsive to child care prices. Through improved data and improved construction of the child care price variable, we find child care price elasticities that are statistically significant, negative and in line with elasticities foun...

2000
G. Chamberlin SG Hall

It is commonly asserted that the standard wage equation derived from bargaining theory cannot be identified. Here, it is argued that the case for this alleged failure rests on an outmoded definition of identification. Newer concepts based on non-stationarities, cointegration and reduced rank are appropriate. An empirical example applying these concepts shows that the standard model can be deriv...

2013
Michihito Ando

In a Regression Kink (RK) design with a finite sample, a confounding smooth nonlinear relationship between an assignment variable and an outcome variable around a threshold can be spuriously picked up as a kink and result in a biased estimate. In order to investigate how well RK designs handle such confounding nonlinearity, I firstly implement Monte Carlo simulations and then study the effect o...

Journal: :The American economic review 2021

This paper uses a direct-projections approach to estimate the effect of capital gains taxation on realizations at state level and then develops framework for determining revenue-maximizing rates federal level. We find that elasticity revenues with respect tax rate over 10-year period is −0.5 −0.3, indicating cuts do not pay themselves 5 percentage point increase would yield $18 $30 billion in a...

2017
Clifford Winston Quentin Karpilow

This paper argues that California’s self-help county tax legislation, which funds additional highway spending, amounts to a natural experiment that can be used to construct a valid instrument to determine highway congestion’s causal effect on the growth rates of GDP, employment, wages, and commodity freight flows for California counties. Our estimation results indicate that highway congestion h...

2009
Timothy J. Bartik

This short paper estimates the state and local fiscal benefits of the Nurse Family Partnership (NFP) program. NFP provides nurse home visiting services to low-income first-time mothers. In addition to social benefits, NFP provides state and local fiscal benefits by reducing costs of social services, welfare, and crime, and increasing tax receipts due to increased earnings of mothers and former ...

2016
Yoshiaki Ohsawa

Policies to harmonize value-added tax rates are controversial in the European Union. This paper formulates a multi-country model over a one-dimensional space as a non-cooperative Nash game, in which each country aims at maximizing its tax revenue, subject to the constraint that its tax rate lies within a given common band. Then we examine the e4ects of changes in the common band on tax rates, t...

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