نتایج جستجو برای: radiation induced sarcoma
تعداد نتایج: 1252440 فیلتر نتایج به سال:
BACKGROUND The relationship between radiation exposure for treatment of cancer and occurrence of a second primary cancer at the irradiated site is well known. This phenomenon is however rare in prostate. CASE PRESENTATION A 75-year-old farmer was treated for rectal cancer with preoperative 45 Gy of radiotherapy and abdominoperineal resection. Four years later he developed symptoms of bladder ...
Background: Pleomorphic Sarcoma is the most common histologic subtype of high grade soft tissue sarcoma involving the extremities. Methods: This retrospective study analyzed 135 patients presenting with primary Pleomorphic Sarcomas which were treated at a single referral institute between 1980 and 2006. Data was collected from an institutional database and univariate and multivariate analysis w...
Ewing sarcomas (ES) harbor a chromosomal translocation that fuses the EWS gene to an ETS transcription factor, most commonly Friend leukemia integration 1 (FLI1). The EWS-FLI1 fusion protein acts in a positive feedback loop to maintain the expression of PARP-1, which is involved in repair of DNA damage. Here, we examine the effects of PARP-1 inhibition and radiation therapy on Ewing sarcomas. I...
We report here the resection of a radiation-induced sarcoma (RIS) of the left clavicle developed in a 59-year-old woman 13 years after radiation for breast cancer. Surgery consisted of extirpation of the tumor with a combined resection of the total layer of the chest wall, the left brachiocephalic vein, and the left subclavian vein, reconstructed with a pediculated musculocutaneous graft using ...
BACKGROUND: Radiation therapy (XRT) is an important modality in the treatment of cancer, and XRT is now commonly utilized in the treatment of early-stage breast cancer. However, its use has occasionally resulted in the development of secondary malignancies. We present a critical review of radiation-induced sarcoma (RIS) that develops after irradiation for the treatment of breast cancer. METHODS...
250 Urology Annals | Jul Sep 2014 | Vol 6 | Issue 3 9. Godlewski J, Maslowski Z, Tenderenda M. Primary osteosarcoma of the urinary bladder. C E J Urol 2009;62:37-8. 10. Akoluk A, Barazani Y, Slova D, Shah S, Tareen B. Carcinosarcoma of the bladder: case report and review of the literature. Can Urol Assoc J 2011;5:E69-73. 11. Chitiyo ME. Primary osteogenic sarcoma of the urinary bladder. J Patho...
PURPOSE Childhood cancer survivors have an increased risk of secondary sarcomas. To better identify those at risk, the relationship between therapeutic dose of chemotherapy and radiation and secondary sarcoma should be quantified. METHODS AND MATERIALS We conducted a nested case-control study of secondary sarcomas (105 cases, 422 matched controls) in a cohort of 14,372 childhood cancer surviv...
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