BACKGROUND Numerous preclinical and clinical studies have reported on the use of platelet concentrates to promote tissue healing. The results in spinal fusion applications are limited and controversial. PURPOSE The purpose of the current prospective clinical cohort study is to assess the effect of Autologous Growth Factors (AGF) on lumbar interbody fusion with specific attention paid to deter...

INTRODUCTION Applying a cross-sectional analysis to a sample of 2,627 African-American and Caucasian adults aged > or = 45 years from the Johnston County Osteoarthritis Project, we studied the association between educational attainment and prevalence of radiographic knee osteoarthritis and symptomatic knee osteoarthritis. METHODS Age- and race-adjusted associations between education and osteo...

better improvements in ODI (P<0.001) and NRS back pain Study Design. Meta-analysis of 4 randomized controlled clinical trials (RCTs). Objective. The aim of the study was to determine if patients with degenerative disc disease who achieve radiographic fusion after single-level lumbar interbody arthrodesis have better clinical outcomes than patients with radiographic pseudarthrosis at 12 and 24 m...

This multicenter study evaluated survivorship, functional outcomes, complications, and radiographic outcomes for patients who underwent total hip arthroplasty using a newly developed highly porous 3-dimensional titanium implant. Excellent aseptic (99.6%) and all-cause (98%) survivorship and functional outcomes were found at 3-year follow-up. This highly porous acetabular shell holds promise in ...

BACKGROUND AIMS Evaluation of: 1. early clinical and radiographic results of total hip arthroplasty (THA) through a standard lateral direct approach, 2. early clinical and radiographic results of THA through a minimal lateral approach, 3. comparison of the results of THA in these two groups. MATERIAL AND METHODS 120 THAs (60 cementless and 60 cemented) done in 120 patients due to degenerat...

We present sessions on establishing key clinical trial outcomes in psoriatic arthritis and on delaying the radiographic progression of ankylosing spondylitis.