Accurate, precise and selective spectrophotometric and spectrofluorimetric methods were developed and subsequently validated for determination of Torasemide (I), Irbesartan (II) and Olmesartan medoxomil (III), where (I) could be determined in presence of its acidic-degradate as stability indicating method, utilizing derivative ratio spectrophotometry, also in human plasma it could be determined...

In this paper, a time fractional diffusion equation on a finite domain is con- sidered. The time fractional diffusion equation is obtained from the standard diffusion equation by replacing the first order time derivative by a fractional derivative of order 0 < a< 1 (in the Riemann-Liovill or Caputo sence). In equation that we consider the time fractional derivative is in...

Simple, accurate, sensitive and validated UV spectrophotometric and chemometric methods were developed for the determination of imidapril hydrochloride (IMD) in the presence of both its alkaline (AKN) and oxidative (OXI) degradation products and in its pharmaceutical formulation. Method A is the fourth derivative spectra (D4) which allows the determination of IMD in the presence of both AKN and...

fractional calculus has been used to model the physical and engineering processes that have found to be best described by fractional differential equations. for that reason, we need a reliable and efficient technique for the solution of fractional differential equations. the aim of this paper is to present an analytical approximation solution for linear and nonlinear multi-order fractional diff...

Simultaneous determination of Dimenhydrinate (DIM) and Cinnarizine (CIN) binary mixture with simple procedures were applied. Three ratio manipulating spectrophotometric methods were proposed. Normalized spectrum was utilized as a divisor for simultaneous determination of both drugs with minimum manipulation steps. The proposed methods were simultaneous constant center (SCC), simultaneous deriva...

A first derivative spectrophotometric (D) and derivative ratio (1DD) methods were utilized to determine raubasine (I) and almitrine dismesylate respectively using methanol as a solvent. A linear relationship was obtained in the range from 6-20 μg ml raubasine for the (D) method and 1024 μg ml almitrine dismesylate for the (DD) method. By applying the proposed methods, it was possible to determi...

The aim of this paper is to study the high order difference scheme for the solution of a fractional partial differential equation (PDE) in the electroanalytical chemistry. The space fractional derivative is described in the Riemann-Liouville sense. In the proposed scheme we discretize the space derivative with a fourth-order compact scheme and use the Grunwald- Letnikov discretization of the Ri...