This study was aimed at preliminarily assessing the cytoprotective and antioxidative effects of rice bran extracts (RBEs) from a Sarawak local rice variety (local name: "BJLN") and a commercial rice variety, "MR219," on oxidative stress in rat H9c2(2-1) cardiomyocytes. The cardiomyocytes were incubated with different concentrations of RBE and hydrogen peroxide (H2O2), respectively, to identify ...

Abstract The purpose of this study was to evaluate the thermal stability rice bran extract (RBE) and analyze effect RBE on shelf-life sunflower oil quality characteristics baked cake. evaluated by a Rancimat test using oil. Properties such as moisture content, porosity, crumb density pore area cakes with synthetic antioxidant butylated hydroxytoluene (BHT) were compared. Sensory properties tast...

The application of fast neutrons, negative pions or heavy ions will only provide an advantage for the radiotherapy of cancer if, in comparison with conventional radiations, e.g., X-rays, gamma rays and electrons, better depth-dose and collimation characteristics or specific radiobiological dose response relationships result in greater local control probabilities for tumours without increased fr...

Bayesian networks (BN) are used in a big range of applications but they have one issue concerning parameter learning. In real application, training data are always incomplete or some nodes are hidden. To deal with this problem many learning parameter algorithms are suggested foreground EM, Gibbs sampling and RBE algorithms. In order to limit the search space and escape from local maxima produce...

BACKGROUND Proton radiotherapy is a form of charged particle therapy that is preferentially applied for the treatment of tumors positioned near to critical structures due to their physical characteristics, showing an inverted depth-dose profile. The sparing of normal tissue has additional advantages in the treatment of pediatric patients, in whom the risk of secondary cancers and late morbidity...

PURPOSE A method was developed to convert clinically prescribed RBE (Relative Biological Effectiveness)-weighted doses from the approach used at the Heavy-Ion Medical Accelerator (HIMAC) at the National Institute of Radiological Science, Chiba, Japan, to the LEM (Local Effect Model)-based TReatment planning for Particles (TRiP98) approach used in the pilot project at the GSI Helmholtzzentrum, D...

Plant organ growth requires the proper transition from cell proliferation to cell expansion and differentiation. The CIN-TCP transcription factor gene TCP4 and its post-transcriptional regulator microRNA319 play a pivotal role in this process. In this study, we identified a pathway in which the product of the C2H2 zinc finger gene RABBIT EARS (RBE) regulates the transcription of TCP4 during Ara...

Charge particle therapy with 12 C ions has the advantage of an enhancement in physical dose distribution due to the Bragg Peak (BP) related to higher Relative Biological Effectiveness (RBE) with respect to X-ray radiotherapy and proton therapy (2.5 for 12 C ions and 1.1 for protons) [1], [2]. The RBE of a 12 C therapeutic beam changes dramatically with depth, especially towards the end of the S...

The manuscript by Gui et al. reports that impaired EGF receptor degradation in the RBE cholangiocarcinoma cell line correlates with a specific reduction in ligand-induced phosphorylation of EGFR Y1045, the recruitment site for c-Cbl. Phosphorylation of receptor tyrosine 1068 is not compromised, so a defect in the kinase activity of the receptor is not to blame. Figure 1 compares the extent of E...