نتایج جستجو برای: rbp2
تعداد نتایج: 96 فیلتر نتایج به سال:
Melanomas are highly heterogeneous tumors, but the biological significance of their different subpopulations is not clear. Using the H3K4 demethylase JARID1B (KDM5B/PLU-1/RBP2-H1) as a biomarker, we have characterized a small subpopulation of slow-cycling melanoma cells that cycle with doubling times of >4 weeks within the rapidly proliferating main population. Isolated JARID1B-positive melanom...
Histone methylation regulates chromatin structure and transcription. The recently identified histone demethylase lysine-specific demethylase 1 (LSD1) is chemically restricted to demethylation of only mono- and di- but not trimethylated histone H3 lysine 4 (H3K4me3). We show that the X-linked mental retardation (XLMR) gene SMCX (JARID1C), which encodes a JmjC-domain protein, reversed H3K4me3 to ...
Although esophageal cancer is highly heterogeneous and the involvement of epigenetic regulation of cancer stem cells is highly suspected, the biological significance of epigenetically modified molecules that regulate different subpopulations remains to be firmly established. Using esophageal cancer cells, we investigated the functional roles of the H3K4 demethylase Jumonji/Arid1b (Jarid1b) (Kdm...
Sorghum (Sorghum bicolor) is mainly grown for stock feed in eastern Australia where significant economic losses result from diseases caused by Fusarium spp. (Petrovic et al., 2009; Kelly 2017). During the 2018 sorghum growing season, 66 plants showing symptoms typical of infection were randomly collected three fields Barramornie (27.08○N, 150.11°E), southern Queensland. isolates obtained surfac...
Our main motivation question is "Is there any relation between the non-coding region and useless error-
 correcting codes?". Then we focused CDS non-CDS areas instead of exon intron, because involves
 in process synthesis a protein involved by exons. We get data genes from NCBI [21].
 In this study, introduce method Fi-noncds that used for determining using
 error-correcting...
Fast neurotransmitter release from ribbon synapses via Ca2+-triggered exocytosis requires tight coupling of L-type Ca2+ channels to release-ready synaptic vesicles at the presynaptic active zone, which is localized at the base of the ribbon. Here, we used genetic, electrophysiological, and ultrastructural analyses to probe the architecture of ribbon synapses by perturbing the function of RIM-bi...
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