Real world data (RWD) and real evidence (RWE) is one of the most rapidly developing areas in modern health care systems, which caused by development technologies for both collecting analyzing data, emergence new sources formation needs regulatory bodies, technology assessment (HTA) agencies, clinical scientific communities. However, at moment, there no universal approach to RWD/E generation app...

In this issue of Blood, Danese and colleagues present a large database analysis of patterns of care and outcomes with respect to chemoimmunotherapy for older patients with chronic lymphocytic leukemia (CLL). Their analysis demonstrates some of the important benefits and limitations of health services research as it relates to hematology.

It is a privilege and a great pleasure to join so many distinguished computer scientists in celebrating the work of Tony Hoare. Tony and I first met when we were both Oxford undergraduates studying the languages of the ancient Greeks and Romans, and their literature, history and philosophy. Tony was two years ahead of me, and even then showed his deep interest in mathematical thought by his app...

Self-sustenance in an unknown environment for an autonomous mobile robot with restricted sensory faculties is a challenging problem, primarily due to lack of effectiveness of existing techniques (deterministic or learning-based) in real world. Through this thesis, we try to investigate the utility of some of the existing reinforcement learning based techniques in achieving energy self-sufficien...

Inspired by an increasing level of social awareness amongst economists which has promoted a movement for ‘Real World Economics’, this paper considers what is required for ‘Real World Language Teaching’. It first discusses issues in the specification of syllabus content, focussing in particular on problems with the proposal for a core English as a Lingua Franca (ELF) syllabus, and possible learn...

Computing at the intersection of two realms. T HE TERM VIRTUAL REALITY USUALLY REFERS TO SYSTEMS THAT generate a totally synthetic environment, in which the end user is able to specify all the characteristics of the new environment. A head-mounted display and an orientation and position tracker enable the user to roam around the new virtual world, look up and down, and walk into rooms that don'...

High quality, virtual 3D models are quickly emerging as a new multimedia data type with applications in such diverse areas as e-commerce, online encyclopaedias, or virtual museums, to name just a few. This paper presents new algorithms and techniques for the acquisition and real-time interaction with complex textured 3D objects and shows how these results can be seamlessly integrated with previ...

It is our great pleasure to welcome you to Drugs: Real World Outcomes, the latest offering from Adis that targets research involving the use of real-world data. We all know that the gold standard in research is the randomized controlled clinical trial; however, we all also know that these trials by the nature of their design fail to inform clinicians on many fronts. While they provide vital con...