نتایج جستجو برای: rearrangement
تعداد نتایج: 27361 فیلتر نتایج به سال:
Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, has various unspecific clinical and histological characteristics. Its early diagnosis is challenging. The application of T-cell receptor (TCR) gene clonal rearrangement to the diagnosis of MF has been widely studied. In this study, we used polymerase chain reaction (PCR) to investigate the diagnostic significance of dete...
To analyze the regulation of gene rearrangement at the T cell receptor (TCR) alpha/delta locus during T cell development, we generated transgenic mice carrying a human TCR delta gene minilocus. We previously showed that the presence of the TCR delta enhancer (E delta) within the J delta 3-C delta intron was required to activate a specific step (V-D to J) of transgene rearrangement, and that rea...
INTRODUCTION ALK gene rearrangement is observed in a small subset (3-7%) of non-small cell lung cancer (NSCLC) patients. The efficacy of crizotinib was shown in lung cancer patients harbouring ALK rearrangement. Nowadays, the analysis of ALK gene rearrangement is added to molecular examination of predictive factors. AIM OF THE STUDY The frequency of ALK gene rearrangement as well as the type ...
We prove the existence of steady 2-dimensional flows, containing a bounded vortex, and approaching a uniform flow at infinity. The data prescribed is the rearrangement class of the vorticity field. The corresponding stream function satisfies a semilinear elliptic partial differential equation. The result is proved by maximizing the kinetic energy over all flows whose vorticity fields are rearra...
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