نتایج جستجو برای: reepithelialization

تعداد نتایج: 374  

Journal: :American journal of physiology. Cell physiology 2012
Chen Zhang Chek Kun Tan Craig McFarlane Mridula Sharma Nguan Soon Tan Ravi Kambadur

Myostatin (Mstn) is a secreted growth and differentiation factor that belongs to the transforming growth factor-β (TGF-β) superfamily. Mstn has been well characterized as a regulator of myogenesis and has been shown to play a critical role in postnatal muscle regeneration. Herein, we report for the first time that Mstn is expressed in both epidermis and dermis of murine and human skin and that ...

2017
Agnes Schwieger-Briel Dimitra Kiritsi Christoph Schempp Cristina Has Hauke Schumann

INTRODUCTION Skin fragility and recurrent wounds are hallmarks of hereditary epidermolysis bullosa (EB). Treatment options to accelerate wound healing are urgently needed. Oleogel-S10 contains a betulin-rich triterpene extract from birch bark. In this study, we tested the wound healing properties of topical Oleogel-S10 in patients with dystrophic EB. METHODS We conducted an open, blindly eval...

Journal: :Journal of refractive surgery 2009
Luca Buzzonetti Gianni Petrocelli Antonio Laborante Emilio Mazzilli Mario Gaspari Paola Valente Elisa Francia

PURPOSE To evaluate epithelial healing, postoperative pain, and best spectacle-corrected visual acuity (BSCVA) after transepithelial photorefractive keratectomy (PRK) performed with a new phototherapeutic keratectomy (PTK) mode using the NIDEK CXIII excimer laser. METHODS Fifteen eyes from 10 patients with myopia underwent transepithelial PRK using a multistage program to perform PTK followed...

2013
Joshua Tam Ying Wang William A. Farinelli Joel Jiménez-Lozano Walfre Franco Fernanda H. Sakamoto Evelyn J. Cheung Martin Purschke Apostolos G. Doukas R. Rox Anderson

BACKGROUND Conventional autologous skin grafts are associated with significant donor-site morbidity. This study was conducted to determine feasibility, safety, and efficacy of a new strategy for skin grafting based on harvesting small columns of full-thickness skin with minimal donor-site morbidity. METHODS The swine model was used for this study. Hundreds of full-thickness columns of skin ti...

Journal: :Acta dermatovenerologica Croatica : ADC 2010
Seyed Jalal Hosseinimehr Ghasemali Khorasani Mohammad Azadbakht Peyman Zamani Maryam Ghasemi Amirhossein Ahmadi

The management of burn injury remains a problem and it is the major cause of death and disability. The aim of this study was to evaluate the efficacy of Aloe vera cream in the treatment of thermal burn wounds and to compare these results with silver sulfadiazine in rats. Animals were divided into four groups. Animals were administered topical cream (Aloe vera powdered gel 0.5% and silver sulfad...

Journal: :Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2007
Andrew Burd Chi H Kwok Siu C Hung Hui S Chan Hua Gu Wai K Lam Lin Huang

Over the past decade, a variety of advanced silver-based dressings have been developed. There are considerable variations in the structure, composition, and silver content of these new preparations. In the present study, we examined five commercially available silver-based dressings (Acticoat, Aquacel Ag, Contreet Foam, PolyMem Silver, Urgotul SSD). We assessed their cytotoxicity in a monolayer...

2014
Gabriel Djedovic Florian Stefan Kamelger Johannes Jeschke Hildegunde Piza-Katzer

Extracorporeal shock wave therapy (ESWT) enhances tissue vascularization and neoangiogenesis. Recent animal studies showed improved soft tissue regeneration using ESWT. In most cases, deep partial-thickness burns require skin grafting; the outcome is often unsatisfactory in function and aesthetic appearance. The aim of this study was to demonstrate the effect of ESWT on skin regeneration after ...

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002
Ryoichi Mori Toshikazu Kondo Tohru Ohshima Yuko Ishida Naofumi Mukaida

To clarify biological roles of tumor necrosis factor receptor p55 (TNF-Rp55) -mediated signals in wound healing, skin excisions were prepared in BALB/c (WT) and TNF-Rp55-deficient (KO) mice. In WT mice, the wound area was reduced to 50% of the original area 6 days after injury, with angiogenesis and collagen accumulation. Histopathologically, reepithelialization rate was approximately 80% 6 day...

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