BACKGROUND In recent years, laryngopharyngeal reflux (LPR) in children has been taken into consideration. OBJECTIVE The aim of this study was to assess the laryngoscopic findings in children diagnosed LPR and/or gastro-oesophageal reflux (GERD). METHODS The findings of 49 patients with at least one or more respiratory complaint such as chronic cough, wheezing, hoarseness, recurrent laryngit...

OBJECTIVE To determine the incidence of biofilm on the vocal fold epithelium of patients with chronic laryngitis. Bacteria can grow in biofilm protected by a glycoprotein mass. Recent studies have shown the importance of biofilm in chronic otolaryngologic infections. Because chronic laryngitis is often recurrent and occasionally purulent, we hypothesized that it is biofilm related. DESIGN Pro...

Gastroesophageal reflux disease (GERD) occurs when acid or other stomach contents back up in the esophagus. The most common symptom of GERD is heartburn, which, while rarely life-threatening, can greatly reduce a patient’s quality of life by affecting daily activities, sleep and what they can eat [1,2]. A systematic review found the prevalence of GERD to be 1020% of the Western world with a low...

It has been suggested that reflux laryngitis (RL) is involved in apneas-bradycardias of the newborn. The aim of the present study was to develop a unique RL model in newborn lambs to test the hypothesis that RL enhances the cardiorespiratory components of the laryngeal chemoreflexes (LCR) in the neonatal period. Gastric juice surrogate (2 ml of normal saline solution with HCl pH 2 + pepsin 300 ...

Background: Inlet patch (IP) lesion is the presence of gastric columnar epithelial tissue outside of the stomach. Symptoms such as a lump in the throat, chronic cough, laryngitis, or other mouth-throat symptoms may be IP-related only and have no other abnormalities. This study aimed to determine the relationship between globus sensation and structural disorder of Inlet Patch in patients with ga...

OBJECTIVE To identify and appraise the evidence for an association between laryngomalacia (LM) and acid reflux through a systematic review of the existing literature. DATA SOURCES MEDLINE, EMBASE, the Cochrane Library, Google Scholar, and collected additional publications cited in bibliographies. REVIEW METHODS Literature search by both authors with structured criteria to select studies eva...

Objective: To provide a synopsis of the various types, causes, and treatments of laryngeal inflammatory conditions. Data Sources: Information contained within this paper was derived from the scientific literature and the clinical experiences of the authors. The data gathered were reinforced by the clinical and research experiences of the authors. Review Methods: The Medline (PubMed) and Cochran...

OBJECTIVE To review the management of gastroesophageal reflux disease (GERD) in adults with esophageal complications (esophagitis, stricture, adenocarcinoma, or Barrett metaplasia) or extraesophageal complications (otolaryngological manifestations and asthma). DATA SOURCES Peer-reviewed publications located via MEDLINE or cross-citation. STUDY SELECTION Emphasis was placed on new developmen...