Regenerating gene family, member 4 (Reg IV), a secreted protein, is overexpressed in several cancers, including gastric cancer (GC). In the present study, we measured Reg IV levels in sera from patients with GC by enzyme-linked immunosorbent assay. We also examined the effect of forced Reg IV expression on the apoptotic susceptibility to 5-fluorouracil (5-FU). Forced expression of Reg IV inhibi...

Preliminary results showed, measurements by rheoencephalography (REG) very promising as a practical, noninvasive continuous monitoring modality of traumatic brain/blast injuries. As the impact of metal fragments on the REG signal is unknown, we report here results of our study .The in vitro study confirmed that impedance pulse amplitude waves do not change in the presence of metal (needles) pla...

This paper investigates a new property of formal languages called \(\mathrm {REG}\)-measurability where {REG}\) is the class regular languages. Intuitively, language \(L\) {REG}\)-measurable if there exists an infinite sequence that “converges” to \(L\). A without has complex shape in some sense so it can not be (asymptotically) approximated by We show several context-free are (including with t...

In the article (Martinez and Zenk, Algebra Universalis, 50, 231–257, 2003.), the authors studied several conditions on an algebraic frame L. In particular, four properties called Reg(1), Reg(2), Reg(3), and Reg(4) were considered. There it was shown that Reg(3) is equivalent to the more familiar condition known as projectability. In this article we show that there is a nice property, which we c...

Intestinal tolerance toward dietary antigens and the microbiota critically depends on regulatory T cells (T(reg) cells). To exert their function, T(reg) cells need to get into the proximity of their target cells foremost within lymphoid organs and the lamina propria in the small and large intestines. Thus, T(reg)-cell-mediated immunosuppression is intrinsically linked to cell migration and loca...

Regenerating islet-derived family, member 4 (Reg IV) is a candidate marker for cancer and inflammatory bowel disease and is associated with neuroendocrine and intestinal differentiation. We have reported that 14% of prostate cancer (PCa) cases are positive for Reg IV by immunohistochemistry. In the present study, we performed immunohistochemical analysis of Reg IV in other major urological canc...

To clarify the role of REG IV, a new member of the regenerating gene (REG) family, in tumorigenesis and progression of colorectal carcinoma (CRC), 320 CRC specimens, 123 corresponding adjacent non-cancerous mucosa (ANCMs), 46 corresponding non-adjacent non-cancerous mucosa (NANCMs) and 86 adenomas were investigated immunohistochemically to compare REG IV expression with clinicopathological feat...

BACKGROUND Impedance plethysmography applied to the head by using a pair of electrodes attached to the scalp surface is known as bipolar Rheoencephalography or REG I and was originally proposed to measure changes in cerebral blood volume related to the heartbeat. REG I was soon discarded in favor of other REG configurations, since most of the signal was shown to be heavily contaminated by the e...

Mast cells promote both innate and acquired immune responses, but little is known about the effect of mast cells on T regulatory (T(reg)) cell function. In this study, we show for the first time that the capacity of murine CD4(+)CD25(+) T(reg) cells to suppress in vitro proliferation by CD4(+)CD25(-) T responder (T(resp)) cells in response to anti-CD3/anti-CD28 mAb-coated beads was reduced in t...