regenerative medicine provides substitutes for organ transplantation, which is restricted in applicability due to immune responses against allograft and the large discrepancy between the need for organs and the number of available transplantation. an artificial environment is allowing cells to induce tissue regeneration. growth factors (gfs) play a significant role in the cell fates in their mi...

BACKGROUND Human cardiac stem cells (CSCs) promote myocardial regeneration in adult ischemic myocardium. The regenerative capacity of CSCs in very young patients with nonischemic congenital heart defects has not been explored. We hypothesized that isolated neonatal-derived CSCs may have a higher regenerative ability than adult-derived CSCs and might address the structural deficiencies of congen...

Muscle satellite cells (SCs) are stem cells that reside in skeletal muscles and contribute to regeneration upon muscle injury. SCs arise from skeletal muscle progenitors expressing transcription factors Pax3 and/or Pax7 during embryogenesis in mice. However, it is unclear whether these fetal progenitors possess regenerative ability when transplanted in adult muscle. Here we address this questio...

recent findings in stem cell biology have opened a new window in regenerative medicine. the endometrium possesses mesenchymal stem cells (mscs) called endometrial stem cells (enscs) having specific regenerative properties linked to adult stem cells. they contribute in tissue remodeling and engineering and were shown to have immuno-modulating effects. many clinical trials were undertaken to asce...

stem cells are self-renewing cells that can be differentiated into other cell types. conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2d) cultures. the design of three-dimensional (3d) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissu...

Regenerative medicine is a complex discipline that becoming hot research topic. Skin, bone, and nerve regeneration dominate current treatments in regenerative medicine. A new type of drug urgently needed for their treatment due to high vulnerability damage weak self-repairing ability. self-assembled peptide hydrogel good scaffolding material because it similar the cytoplasmic matrix environment...

Perez-Terzic C, Childers MK: Regenerative rehabilitation: a new future? Am J Phys Med Rehabil 2014;93(Suppl):S73YS78. Modern rehabilitation medicine is propelled by newfound knowledge aimed at offering solutions for an increasingly aging population afflicted by chronic debilitating conditions. Considered a core component of future health care, the rollout of regenerative medicine underscores a ...