Objective Genetic and morphologic similarities between mouse embryonic stem cell (ESCs) and Primordial Germ Cell (PGCs) make it difficult to distinguish the two cell types in in vitro differentiation. Using the expression of specific markers of germ cells that are not expressed or expressed at low levels in ESCs, can help recognizing in vitro differentiated cells MaterialsAndMethods In this stu...

Abstract Background Streptococcus suis type 2 (SS2) is an important zoonotic pathogen. We have previously reported the structure of LuxS protein and found that luxS gene closely related to biofilm, virulence expression drug resistance SS2. However, mechanism mediated SS2 stress response unclear. Therefore, this experiment performed mutant (Δ ) complement strain ( C Δ ), overexpression +) wild-t...

background: peroxisome proliferator activated receptor gamma (pparγ), a member of nuclear receptor superfamily, comprises two isoforms in mouse. these two isoforms are encoded by different mrnas, which are arisen by alternative promoter usage. there are two promoter regions upstream of pparγ gene. a 3 kb fragment, containing several transcription factor binding sites, acts as pparγ1 promoter re...

background  recent investigations show that both proliferation and secretion of macromolecules by cells can be regulated by low level laser therapy (lllt). the aim of this study was to determine whether lllt could induce a bio-stimulatory effects on human gingival fibroblasts (hgf3-pi 53). therefore, the effect of laser irradiation on human gingival cell proliferation and collagen type i gene e...

Exercise is cardioprotective, though optimal interventions are unclear. We assessed duration dependent effects of exercise on myocardial ischemia-reperfusion (I-R) injury, kinase signaling and gene expression. Responses to brief (2 day; 2EX), intermediate (7 14 7EX 14EX) extended (28 28EX) voluntary wheel running (VWR) were studied in male C57Bl/6 mice. Cardiac function, I-R tolerance survival ...