Background and Aims: Thyroid hormones have an important role in metabolism and regulation of the red blood cells (RBCs). Thyroid dysfunction induces various effects on blood cells such as anemia through reducing the oxygen metabolism. For the first time, we aimed to determine the effects of severity activation of hypothyroidism on RBCs indices in patients with hypothyroidism. Materials and Met...

aim : evaluation of biological characteristics of 13 identified proteins of patients with cirrhotic liver disease is the main aim of this research.   background : in clinical usage, liver biopsy remains the gold standard for diagnosis of hepatic fibrosis. evaluation and confirmation of liver fibrosis stages and severity of chronic diseases require a precise and noninvasive biomarkers. since the...

osteoporosis is a systemic skeletal disease and there is a close relationship between the sympathetic nervous system (sns) and bone metabolism. leptin has been shown to regulate bone formation and bone resorption via the sns. however, the effect of sns on leptin signaling has not been clearly understood. in the present study, we studied the effect of propranolol on ovariectomy-induced osteoporo...

The adipose cell maintains a central role in the regulation of lipid metabolism (Galton, 1971). It contains the largest store of triglyceride and cholesterol in the body; it is the only source of plasma fatty acids, a major oxidative fuel, particularly in the fasting state, and it is the major site of clearance of chylomicrons and very-low-density lipoprotein (VLDL) in the fed state. The import...

objective: micrornas (mirnas) are noncoding rnas that function as key regulators of diverse biological activities such as cellular metabolism, cell proliferation and cell cycle regulation. recent studies have indicated the high potential of these small molecules to control stem cell differentiation into desired cells. the aim of present study is to investigate the possible effect of let-7f on e...

Abstract Bacteria produce diverse d-amino acids, which are essential components of cell wall peptidoglycan. Incorporation these acids into peptidoglycan contributes to bacterial adaptation environmental changes and threats. d-Amino have been associated with growth, biofilm formation dispersal regulation metabolism. The diversity in bacteria is primarily due the activities amino acid racemases t...