Recent high-profile studies report GDF11 to be a key circulating 'anti-aging' factor. However, a screen of extracellular proteins attempting to identify factors with 'anti-aging' phenotypes in aged murine skeletal muscle satellite cells did not identify GDF11 activity. We have been unable to confirm the reported activity of GDF11, similar to other laboratories offering conflicting data and desc...

Rejuvenators improve the performance of reclaimed asphalt mixtures but relatively little is known about their long-term aging characteristics. This study evaluated effect four different rejuvenators on characteristics 100% mixtures. Rheological tests extracted bitumen revealed that tall oil-based rejuvenator showed highest reduction and petroleum-based lowest in stiffness binder long term. At l...

Bio-oil recycled asphalt binders in road engineering can help solve the problem of oil shortage and reduce environmental pollution sustainability. This paper investigated performance aged binder by adding bio-oil so that could be reused to reach purpose reuse. The residual soybean was selected as rejuvenator blended with at 0%, 2%, 4%, 6%, respectively. results showed increased penetration bind...

BACKGROUND Makaradhwaja a gold containing mercurial preparation used for diabetes mellitus in indigenous system of medicine. It is a popular aphrodisiac and rejuvenator traditional medicine. It is prepared by using processed gold, mercury and sulfur in different ratios by applying intermittent heating pattern in Valuka Yantra. OBJECTIVES The aim of the study was to evaluate anti-diabetic effe...

There is a need for effective nutraceuticals for osteoarthritis care. The fruit of Phyllanthus emblica is used as a powerful rejuvenator in Ayurvedic medicine. This study measured the chondroprotective potential of P. emblica ('Amalaki') fruits in vitro. We used aqueous extracts of unprocessed P. emblica fruit powder (powder A), and the powder obtained after hot water extraction and drying of p...

Asphalt recycling technology with a high content of reclaimed asphalt pavement (RAP) is becoming more important as the price paving materials rises and sustainable development environmental conservation rules become rigorous. Nevertheless, road authorities in numerous countries still prohibit utilisation RAP mixes due to negative impacts on performance mixtures. Consequently, different rejuvena...

The utilization of reclaimed asphalt pavement (RAP) contributes significantly to reducing resource waste and protecting the environment. However, due performance rejuvenator, fatigue cracking has always been one important constraint on development pavements. Based studies previously conducted by our group, this paper investigated properties rubber/oil (WRO) rejuvenated common dynamic shear rheo...

The compatibility potential of rejuvenators plays an important role in improving the blending degree rejuvenated bitumen. This study aims at estimating efficiency molecular dynamics (MD) simulation predicting between and aged bitumen, exploring influence rejuvenator type, aging temperature on potential. thermal storage stability binders is evaluated to validate prediction. Afterward, underlying...