This paper addresses the expression of the epidermal growth factor (EGF) gene by human breast tumor biopsy samples. Northern analysis was used to demonstrate the presence of an approximately S-kilobase inR.NA which specifically hybridized with radiolabeled human EGF complementary DNA in some human breast tumor biopsy samples. Quantitation of EGF niKN'A in 60 human breast tumor biopsies using th...

multiple sclerosis is a chronic inflammatory disease of the central nervous system characterized by a complex immune response. because of the complex nature of ms pathogenesis, a panel of biomarkers derived from different platforms will be required to reflect disease-related alterations. monitoring and evaluation of molecules associated with the pathogenesis of the disease would provide useful ...

interest in hydroxy - carboxylic acid 2 (hca2) receptor has been raised since it is the target of antidyslipidemic drug nicotinic acid. the present study aimed to evaluate the presence of mrna of this receptor in different organs of laboratory rat. twenty two different organs of rats including mesenteric fat, epididymis (head, body and tail), testis, ovary, xiphoid process, liver, adrenal gland...

runx3, a member of runt-related transcription factor (runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. in the present study, exogenous run3 was transiently expressed in ags (human gastric adenocarcinoma), with undetectable runx3 protein and in a549 (human lung carc...

Booster vaccination with messenger RNA (mRNA) vaccines has been offered to adults in England starting on 14 September 2021. We used a test-negative case–control design estimate the relative effectiveness of booster dose BNT162b2 (Pfizer-BioNTech) compared only two-dose primary course (at least 175 days after second dose) or unvaccinated individuals from 13 2021 5 December 2021, when Delta varia...

leptin is secreted mainly by fat, which is involved in energy metabolism and reproduction. leptin and itsreceptor (ob-r) have been detected in human spermatozoa and testis, thus it can be concluded leptin involves in male physiology. the goal of this study was determination of the presence of leptin receptor mrna in the ram testis, epididymis and spermatozoa by reverse transcription polymerase ...