Distal renal tubular acidosis is a syndrome of abnormal urine acidification and is characterized by hyperchloremic metabolic acidosis, hypokalemia, hypercalciurea, nephrocalcinosis and nephrolithiasis. Despite the presence of persistent hypokalemia, acute muscular paralysis is rarely encountered in males. Here, we will report an eighteen year old male patient who presented with flaccid quadripa...

In two infants with distal renal tubular acidosis phosphate depletion was observed in the extracellular and intracellular compartments of the erythrocytes. Treatment corrected this disturbance over a period of several months. Cell phosphate deficiency may contribute to the adverse effects of renal tubular acidosis on bone.

A four day old female infant was admitted because of poor feeding, vomiting and jaundice. Laboratory examination showed hyperkalemia, mild hyponatremia and renal tubular acidosis type 4. Serum aldosterone and plasma renin activity were elevated but serum cortisol, 17 -hydroxyprogesterone, ACTH, 24 hour urinary 17- ketoste roid, pregnanetriol, renal function and sonogram were normal and henc...

Renal Tubular Acidosis (RTA) is a clinical syndrome characterised by metabolic acidosis secondary to a disorder in renal acidification. The acidification may be manifested by a defect in the renal tubular reabsorption of bicarbonate and/or urinary excretion of hydrogen ion1 -3. In terms of clinical and physiopathological aspects this disease can be classified into three groups: distal RTA or ty...

The discovery of a case of renal tubular acidosis and fibrosing alveolitis led to the investigation of 19 further patients. Abnormal pulmonary function tests were found in a further four patients with overt renal tubular acidosis and in four out of eight patients with "incomplete" renal tubular acidosis. The response to an ammonium chloride test in seven patients with cryptogenic fibrosing alve...

INTRODUCTION Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus erythematosus complicated by type 4 renal tubular acidosis who did not do poorly. CASE PRESENTA...

proximal weakness specially in extremitas is a common neurologic symptom of patients, for which the physician should consider toxic, metabolic, infectious and paraneoblastic diseases affecting muscular system as well as primary myopathies. osteomalacia is one of the most common considerations which is treatable but disabling as its natural course. osteomalacia is the most often due to vitd or c...