INTRODUCTION The purpose of this study was to evaluate the effects of risedronate (Ris) in the modulation of bone formation in rats with glucocorticoid (GC)-induced osteoporosis by histomorphometric, immunohistochemical and gene expression analyses. METHODS We analyzed structure, turnover and microarchitecture, cyclooxygenase 2 (COX-2) levels and osteocyte apoptosis in 40 female rats divided ...

Abstract Sometimes, a rather high stress drop characterizes earthquakes induced by underground fluid injections or productions. In addition, long-term operations in the can influence seismogenic reaction of rock per unit volume involved. The index is quantitative characteristic such reaction. We derive relationship between and drop. This shows that increases with average seismicity. Further, we...

A series of Mb 3.8-5.5 induced seismic events in the midcontinent region, United States, resulted from injection of fluid either into a basal sedimentary reservoir with no underlying confining unit or directly into the underlying crystalline basement complex. The earthquakes probably occurred along faults that were likely critically stressed within the crystalline basement. These faults were lo...

Abstract We reanalysed the induced seismicity data from Groningen gas reservoir. used well-maintained event catalogue of KNMI. The distributions seismic moments and interevent times show a power law behaviour over several decades, we find that upon increasing magnitude threshold, these remained scale-invariant. Because this scale-invariance, can put constraint on average loading elastic energy ...

The standard model of injection-induced seismicity considers changes in Coulomb strength due solely to changes in pore pressure. We consider two additional effects: full poroelastic coupling of stress and pore pressure, and time-dependent earthquake nucleation. We model stress and pore pressure due to specified injection rate in a homogeneous, poroelastic medium. Stress and pore pressure are us...

We present statistical evidence for a temporal link between variations in the El Niño-Southern Oscillation (ENSO) and the occurrence of earthquakes on the East Pacific Rise (EPR). We adopt a zero-inflated Poisson regression model to represent the relationship between the number of earthquakes in the Easter microplate on the EPR and ENSO (expressed using the southern oscillation index (SOI) for ...

Abstract The development and application of enhanced geothermal system hydrothermal are constrained due to high cost risk induced seismicity or heavily reliance on hot water reservoir. Deep borehole heat exchanger (DBHE) technology is independent reservoir hydraulic fracturing; however, the poor thermal conductivity rocks limits its performance improvement. To deal with these problems, a novel ...

PURPOSE Evidence has accumulated in recent years suggestive of a genetic basis for a susceptibility to the development of radiation injury after cancer radiotherapy. The purpose of this study was to assess whether patients with severe radiation-induced sequelae (RIS; i.e., National Cancer Institute/CTCv3.0 grade, > or =3) display both a low capacity of radiation-induced CD8 lymphocyte apoptosis...