Research and higher education are facing an on-going transformation of practice resulting in the need for effective collaboration and sharing of resources within and across disciplinary and geographical boundaries. Portal technologies and portal-based virtual research and learning environments (VREs and VLEs) already have become standard infrastructures within a large number of research communi...

The vanM gene was first found in a vancomycin-resistant Enterococcus faecium (VREm) isolate in Shanghai in 2006. In this study, we found that, in 70 VREm strains isolated in nine Shanghai hospitals from 2006 to 2014, vanM was more prevalent than the vanA gene (64.3% [45/70] versus 35.7% [25/70]). The vanM-type isolates showed similar antimicrobial susceptibility patterns with the vanA types. Th...

Vancomycin-resistant Enterococcus faecium has emerged as a multidrug-resistant pathogen in hospital settings. Here, we present the draft genome sequence of a high-level vancomycin-resistant strain, E. faecium ATCC 51559, which is employed as a standard laboratory vanA genotype-positive control strain for clinical and laboratory studies.

Hospitals in the United States are under increasing pressure to perform active surveillance cultures for detection of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) among newly admitted patients. Results of such cultures can then be used to direct contact precautions to prevent transmission of MRSA and VRE in the health care setting. However, using...

Oritavancin is in the final stages of clinical development for treatment of acute bacterial skin and skin structure infections. This drug has demonstrated potent activity against staphylococci (minimum inhibitory concentration [MIC] for which 90% of isolates are inhibited [MIC(90)], 0.06 μg/mL), enterococci (MIC(90), ≤ 0.008 to 0.5 μg/mL), and streptococci (MIC(90), ≤ 0.008 to 0.12 μg/mL), incl...

INTRODUCTION Vancomycin resistant and multi-drug-resistant enterococci are the major emerging pathogens in surgical, neonatal, and tertiary care units. METHODOLOGY In this study, 267 enterococci from different clinical and non-clinical samples of equine origin were tested for their antimicrobial drug sensitivity against 19 antimicrobials using disc diffusion method. RESULTS A total of 80.2%...

Background: Enterococci faecalis are predominating species of Enterococci causing nosocomial infections. Acquisition of resistance to antibacterial agents, and ability to transfer the resistant genes made them clinically important. This study was performed to determine the frequency of isolation of different species of Enterococci, and the antibacterial resistance pattern of the isolated specie...

Introduction: Enterococci are gram-positive coccoid bacteria that are present in the normal flora of the gastrointestinal tract in human, and many mammals and birds, as well as the environment. Vancomycin-resistant Enterococci (VRE) are a major and rising problem in hospitals throughout the world. The present study aimed to investigate the frequency of strains of Enterococci and the pattern of ...

High level aminoglycoside resistance is an established phenomenon in enterococci. With the increasing use of broad spectrum cephalosporins and glycopeptides, vancomycin resistant enterococci are being increasingly reported from different parts of the world. The objective of our study was to determine the prevalence of high level gentamicin resistant (HLAR) enterococci among the clinical isolate...