Background: Resistance of Mycobacterium Tuberculosis is a condition in which Anti-Tuberculosis (OAT) drugs are unable to kill the germs. One type resistance Multidrug Resistant Tuberculosis. (MDR-TB) TB caused by bacteria that resistant 2 types OAT, namely INH and Rifampin. The consequences if OAT deterioration health, increased costs, prolonged treatment, high rates therapy failure death.&#x0D...

The magnitude of problem with tuberculosis lies in the fact that one third of the world population is infected by Mycobacterium tuberculosis. Even in the 21st century, tuberculosis kills more people than any other infective agent. Definition of case of resistance--the case of resistant tuberculosis is precisely defined by the recommendations of the World Health Organization as primary, initial,...

Tuberculosis (TB) remains a major global health problem, particularly in many of the developing countries including India. Some of the factors that have substantially contributed to the number of multi-drug resistant tuberculosis (MDRTB) and extensively drug resistant tuberculosis (XDRTB) cases both in general and among HIV infected persons arethe delay in the diagnosis as well as delayed deter...

TO THE EDITOR—How does the global community gain more traction in an effort to combat multidrug-resistant (MDR) tuberculosis globally? We have considered whether it would be helpful to address MDR tuberculosis as a separate epidemic. We introduced the idea because the dominant strategy globally for the past 2 decades has been based on the premise that MDR tuberculosis could be controlled by str...

Introduction: Tuberculosis is one of the most common diseases in developing countries, resulting in significant morbidity and mortality. Tuberculosis has varied clinical presentations, varying from common primary pulmonary tuberculosis to the extremely rare tubercular otitis externa, as in this case. Tubercular otitis externa has an extremely low clinical incidence.   Case Report: We report the...

multidrug-resistant (mdr) and extensively drug-resistant (xdr) tuberculosis (tb) are increasing globally. treatment options for these patients are very limited. although treatment of these patients with standardized regimen is associated with high mortality and morbidity, rational usage of new drugs might be promising. in this study we will review epidemiology of xdr-tb and tdr-tb in iran and t...

BACKGROUND The increasing prevalence of drug-resistant tuberculosis and the threat of extensively-drug-resistant tuberculosis in HIV hotspots have made the detection and treatment of drug-resistant tuberculosis in the sub-Saharan Africa setting a global public health priority. OBJECTIVE We sought to examine the impact and challenges of tuberculosis diagnostic capacity development for the dete...

background: tuberculosis is one of the infectious diseases worldwide that has resurgence by the aids epidemic and led to the rise of drug-resistant tuberculosis patients. thus, it seems essential to monitor the drug susceptibility in tuberculosis patients. the new high resolution melting (hrm) method is simple, rapid and inexpensive for detection of the mutations responsible for drug resistance...

amikacin has been shown to irreversibly suppresscochlear activity.the aim of this study is to assess the incidence of amikacinototoxicity in multidrug-resistant tuberculosis patients and riskfactors associated withthis ototoxicity.in this cross-sectional study, 41 patientswith multidrug-resistant tuberculosis (mdr-tb) were included.all patients received fixed dose of intravenous amikacin(500 mg...

background there is limited data on outcomes of adolescents with drug-resistant tuberculosis (dr-tb). objectives to describe patient outcomes and factors associated with outcomes of adolescents diagnosed with dr-tb in khayelitsha, south africa. patients and methods a retrospective analysis of data for adolescents aged 10-19 years who were diagnosed with dr-tb between january 2008 and august 201...