BACKGROUND AND PURPOSE The need for target adjustment due to respiratory motion variation and the value of carina as a motion surrogate is evaluated for locally advanced non-small-cell lung cancer. MATERIAL AND METHODS Using weekly 4D CTs (with audio-visual biofeedback) of 12 patients, respiratory motion variation of primary tumors (PT), lymph nodes (LN) and carina (C) were determined. RESU...

A case of ataxia telangiectasia in a 7 year-old boy associated with Hodgkin disease was presented. Abnormalities of motion along with repeated respiratory tract infections requiring hospitalization started when he was 2 years old. The patient was placed on MOPP protocol Hodgkin treatment in addition to replace­ment therapy as advised. 

In image-guided lung intervention, the electromagnetic (EM) tracked needle can be visualized in a pre-procedural CT by registering the EM tracking and the CT coordinate systems. However, there exist discrepancies between the static pre-procedural CT and the patient due to respiratory motion. This paper proposes an online 4-D CT estimation approach to patient-specific respiratory motion compensa...

Respiratory motion is traditionally assessed using tumor motion magnitude. In proton therapy, respiratory motion causes density variations along the beam path that result in uncertainties of proton range. This work has investigated the use of water-equivalent thickness (WET) to quantitatively assess the effects of respiratory motion on calculated dose in passively scattered proton therapy (PSPT...

OBJECTIVE To assess the feasibility of renal proton magnetic resonance spectroscopy for quantification of triglyceride content and to compare spectral quality and reproducibility without and with respiratory motion compensation in vivo. MATERIALS AND METHODS The Institutional Review Board of our institution approved the study protocol, and written informed consent was obtained. After technica...

The development of methods for correcting patient motion in emission tomography has been receiving increased attention. Often the performance of these methods is evaluated through simulations using digital anthropomorphic phantoms, such as the commonly used extended cardiac torso (XCAT) phantom, which models both respiratory and cardiac motion based on human studies. However, non-rigid body mot...

INSERM UMR1101, LaTIM, Brest, France Respiratory motion in PET/MR imaging leads to reduced quantitative and qualitative image accuracy. Correction methodologies include the use of respiratory synchronized gated frames which lead to low signal to noise ratio (SNR) given that each frame contains only part of the count available throughout an average PET acquisition. In this work, 4D MRI extracted...

Cardiovascular magnetic resonance (CMR) imaging has emerged as an important research tool for studies of ischemic heart disease due to its versatility, relatively low cost, and high image quality that allows accurate and reproducible quantification of cardiac structure and function. However, while imaging of cardiac function and myocardial viability (and to some extend imaging of the coronary a...

King’s College London, Division of Imaging Sciences and Biomedical Engineering, London, UK The impact of respiratory motion correction on quantitative accuracy in PET imaging is evaluated using real-time simulations for variable patient specific characteristics such as tumor malignancy and respiratory pattern. Respiratory patterns from real patients were acquired, with long quiescent motion per...