Lightweight steel framing is a method in housing and construction that have been widely used in lightweight steel construction. In this method, the structure is built by cold formed steel elements. They are cost-effective, light, and easy to assemble. However, the performance of lateral load resisting systems in cold-formed steel structures specially the behavior of cold-formed steel shear wall...

This paper proposes a technique for developing parametric models of modally degenerate resonators from stimulus-response data. The complements traditional empirical frequency response estimates that are commonly used testing MEMS resonators, however, the have distinct advantages when modal differences close enough to frustrate quality factors, natural frequencies and mode orientations. proposed...

SUMO (small ubiquitin-related modifier) modification is emerging as an important post-translational control in transcription. In general, SUMO modification is associated with transcriptional repression. Although many SUMO-modified transcription factors and co-activators have been identified, little is known about the mechanism underlying SUMOylation-elicited transcriptional repression. Here, we...

BACKGROUND Home modification for stroke victims is often necessary to prevent falls and enable them to have a better quality of life. Up-to-date relationship between personal factors and home modifications in post-stroke patients has not been investigated. OBJECTIVE To identify significant personal factors influencing the requirement for home modification in post-stroke patients. STUDY DESI...

Transcription factor activity is largely regulated through post-translational modification. Here, we report the first integrative model of transcription that includes both interactions between transcription factors and promoters, and between transcription factors and modifying enzymes. Simulations indicate that our method is robust against noise. We validated our tool on a well-studied stress r...

BACKGROUND Negative attentional biases are thought to increase the risk of recurrence in depression, suggesting that reduction of such biases may be a plausible strategy in the secondary prevention of the illness. However, no previous study has tested whether reducing negative attentional bias causally affects risk factors for depressive recurrence. The current experimental medicine study repor...