OBJECTIVE To determine whether injuries to sub-optimally restrained child occupants in real-world crashes were likely to be preventable by alternative restraint usage practices and to assess the usefulness of crash reconstruction for exploring injury mechanisms in child occupants. METHODS Real-world crashes in which child occupants sustained significant injuries were reconstructed on a labora...

The Robust Project aims to improve scientific and technical knowledge on the main issues still open in the new European standards on road restraint system EN 1317 [1-2]. The knowledge acquired will form the basis of updated standards for EN1317 and lead to more advanced road restraint systems and improve road-users safety. This report is part of the deliverables from Work Package 5 (WP5)-Comput...

BACKGROUND General aviation accidents involving children are rare, but when they do happen, little is known about the children involved, including their age, restraint status, and injuries. This lack of information is due to the fact that the National Transportation Safety Board (NTSB) did not always collect detailed data about passengers involved in accidents. METHODS Consequently, in 2011, ...

Histamine as a neurotransmitter participates in modulation of pain transmission within the central nervous system. Exogenous histamine administered intracerebroventricularly (icv) as well as endogenous histamine, after blockage of its catabolism by histamine N-methyltransferase (HNMT) inhibitors, which leads to an increase in endogenous histamine concentrations, produce an antinociceptive effec...

While there are clear racial/ethnic disparities in child restraint system (CRS) use, to date no studies have identified mediators that quantitatively explain the relationship between race and CRS u...

Many efforts to develop walking and running robots utilize a boom or other device to catch the robot when it falls, sense the position of the robot, and constrain the robot to operate in a two dimensional plane. However, publications usually focus on the robot, and the restraint system remains undocumented. Each group must start from scratch, or rely on word of mouth to build on the experience ...

BACKGROUND Ventricular restraint is a nontransplantation surgical treatment for heart failure. The effect of varying restraint level on left ventricular (LV) mechanics and remodeling is not known. We hypothesized that restraint level may affect therapy efficacy. METHODS AND RESULTS We studied the immediate effect of varying restraint levels in an ovine heart failure model. We then studied the...

During the past 40 years, different child restraint systems (CRS) have been developed to improve protection for children of different sizes and ages. Development of more effective CRS, and a higher frequency in use of the restraints, in addition to enhanced vehicle safety, has resulted in an increased level of child safety. This study examines accident data with Volvo cars in Sweden to evaluate...

Use of restraint chairs by law enforcement for violent individuals has generated controversy and a source of litigation because of reported injuries and deaths of restrained subjects. The purpose of this study is to review the available medical and legal literature and to allow the development of evidence-based, best practice recommendations to inform the further development of restraint chair ...