The aim of this study was the prediction model retention indices compounds from aboveground parts Achillea clypeolata Sibth. & Sm. essential oil, obtained by hydrodistillation and analysed GC?MS. quantitative structure?retention relationship analysis applied in order to anticipate time compounds. selection seven molecular descriptors done a genetic algorithm. chosen were uncorrelated used c...

Abstract Bacterial DNA gyrase and topoisomerase IV control the topological state of during replication represent important antibacterial drug targets. To be successful as candidates, newly synthesized compounds must possess optimal lipophilicity, which enables efficient delivery to site action. In this study, retention behavior twenty-three previously dual inhibitors was tested in RP-HPLC syste...

A novel analytical approach involving the addition of an ionic liquid into the mobile phase of the thin-layer chromatography (TLC) system during the optimization of chromatographic separation of peptides was demonstrated. Different behavior of peptides in the TLC sytem was observed after the addition of 1,3-dimethylimidazolium methyl sulfate to the eluent in comparison to the system without the...

The transcriptional regulator QsrR is converted into a genetically encoded fluorescent probe capable of ratiometric monitoring of quinones in living cells with high sensitivity and selectivity.

customer activity has received more attention due to the increase of social network applications. moreover, customer activity could be an answer to the research debate about the significant relationship between retention rate and lifetime profitability of customers. several researchers believe that an increase in the retention rate of customers may enhance their customer lifetime value (clv), o...