Serum copper, serum caeruloplasmin, and urinary copper excretion were measured in 38 American patients (and 15 family members) with recessive, dominant, and X-linked forms of retinitis pigmentosa. No abnormalities were found, in contrast to the findings of a recent study on Indian patients. Our data argue against a role for copper metabolism in ordinary retinitis pigmentosa.

This study was made on 100 patients with retinitis pigmentosa and 23 of their relatives. Their plasma, erythrocyte, and hair Zn and serum Cu levels were compared with those of a control group of 14 healthy persons. No statistically significant difference in these levels was found between the patients with retinitis pigmentosa and the relatives or controls.

(1) HISTORICAL.-In the fully-developed state, choroideremia presents a characteristic and unmistakable picture of which Fig. 1 and Colour Plate 1(a and b) may be taken as examples. The almost total lack of choroidal vessels strongly suggests a developmental anomaly. In fact most of the early writers on, the subject, such as Mauthner (1872) and Koenig (1874), stressed the likeness to choroidal c...

A brother and sister, children of normal parents are described. They had retinitis pigmentosa, causing near-blindness as a result of very narrow fields of vision, associated with metaphyseal chondrodysplasia and marked shortening of the metacarpals and terminal phalanges. Autosomal recessive inheritance is suggested with a common biochemical cause for all these defects. This apparently new asso...

A thirteen years old male patient of i was referred to our Dermatology D knees and hands. Patient was blind since birth and diagnosis of “retinitis pigmentosa” Ophthalmology Department. He was investigated and found raised levels of blood sugar, triglycerides, VLDL, TSH, SGOT/PT and kidney functions tests. He was diagnosed as a case of eruptive xanthomas with retinitis pigmentosa in secondary h...

Retinitis pigmentosa affects 50,000-100,000 people in the United States and about 1.5 million people worldwide. Patients usually report impaired adaptation, night blindness, and loss of mid-peripheral visual field in adolescence. As the condition progresses, they lose far-peripheral visual field and eventually lose central vision as well. Some patients have become blind as early as age 30. The ...