*Corresponding Author: Dr. Sumit Sethi, Ph.D. Interdisciplinary Laboratory for Clinical Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo UNIFESP, Building Research II, São Paulo, SPBrazil. 4022 PHYSIOLOGICAL EVIDENCE OF AN INVERSE CORRELATION BETWEEN THE GONADAL FUNCTION AND RFRP-3 NEURONS IN MICE Sumit Sethi* and Chandra Mohini Chaturvedi Interdisciplinary Labor...

early in the development of many animals, before transcription begins, any change in the pattern of protein synthesis is attributed to a change in the translational activity or stability of mrna in the egg and early embryo. as a result, translational control is critical for a variety of developmental decisions, including oocyte maturation and initiation of preimplantation development. in this s...

The Neuropeptide FF receptor family contains two subtypes, NPFF1 and NPFF2 (provisional nomenclature [12]), which exhibit high affinities for neuropeptide (NPFF, O15130) RFamide related peptides (RFRP: precursor gene symbol NPVF, Q9HCQ7). is broadly distributed in the central nervous system with highest levels found limbic hypothalamus. present density superficial layers of mammalian spinal cor...

PURPOSE Computer-assisted sampling of EST data contained within the UniGene human sequences collection is being used to establish a catalog of novel genes that are expressed exclusively or predominantly in the human retina. This provides a valuable source for candidate genes possibly involved in retinal degeneration. In this report we present the characterization of the C7orf9 gene locus encodi...

Recently, kisspeptin (KP) and gonadotropin inhibitory hormone (GnIH), two counteracting neuropeptides, have been acknowledged as significant regulators of reproductive function. KP stimulates reproduction while GnIH inhibits it. These two neuropeptides seem to be pivotal for the modulation of reproductive activity in response to internal and external cues. It is well-documented that the current...